1-(2-Iodophenyl)-1H-tetrazole as a ligand for Pd (II) catalyzed Heck reaction

AK Gupta, CH Song, CH Oh

文献索引：Gupta, Arun Kumar; Song, Chung Hyun; Oh, Chang Ho Tetrahedron Letters, 2004 , vol. 45, # 21 p. 4113 - 4116

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被引用次数: 86

摘要

1-(2-Iodophenyl)-1H-tetrazole 2 was synthesized by the reaction of 2-iodoaniline, sodium azide and triethyl orthoformate in acetic acid. The newly synthesized ligand 2 was successfully used in Heck reaction to give the cross-coupled products in excellent yields. ... An active catalyst for Heck reaction by combination of Pd(OAc) 2 with the new ligand, 1-(2-iodophenyl)-1H-Tetrazole (2), was developed. ... In view of the optimization of the reaction conditions, we have ...