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347370-91-6 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Calcium-activated potassium channel subunit alpha-1
External ID: CHEMBL954137
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2009
Volume: 17
Issue: 1
First Page: 319
Last Page: 325
DOI: 10.1016/j.bmc.2008.10.068

Target ChEMBL ID: CHEMBL4304
ChEMBL Target Name: Calcium-activated potassium channel subunit alpha-1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
17.378IC50=17378.01nM
17.7828IC50=17782.79nM
18.6209IC50=18620.87nM
30.1995IC50=30199.52nM
30.903IC50=30902.95nM
154.882IC50=154881.66nMOutside typical range
26.9154IC50=26915.35nM
0.37154IC50=371.54nM
2.13796IC50=2137.96nM
2.51189IC50=2511.89nM
3.46737IC50=3467.37nM
8.70964IC50=8709.64nM
11.2202IC50=11220.18nM
12.5892IC50=12589.25nM
13.4896IC50=13489.63nM
13.8038IC50=13803.84nM