HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3232201

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1979
Volume: 22
Issue: 2
First Page: 134
Last Page: 150
DOI: 10.1021/jm00188a005

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.36	C50	=	0.36	uM
0.61	C50	=	0.61	uM
0.8	C50	=	0.8	uM
0.25	C50	=	0.25	uM
80	C50	=	80	uM
0.23	C50	=	0.23	uM
0.84	C50	=	0.84	uM
0.46	C50	=	0.46	uM
0.64	C50	=	0.64	uM
1.71	C50	=	1.71	uM
1.35	C50	=	1.35	uM
0.9	C50	=	0.9	uM
14	C50	=	14	uM
12	C50	=	12	uM
2.7	C50	=	2.7	uM
11	C50	=	11	uM
1.9	C50	=	1.9	uM
2.6	C50	=	2.6	uM
0.91	C50	=	0.91	uM
0.9	C50	=	0.9	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：L1210

External ID: CHEMBL3232194

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1979
Volume: 22
Issue: 2
First Page: 134
Last Page: 150
DOI: 10.1021/jm00188a005

Target ChEMBL ID: CHEMBL386
ChEMBL Target Name: L1210
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
log(ILSmax)	=	1.89
log(ILSmax)	=	2.04
log(ILSmax)	=	1.62
log(ILSmax)	<	1.4
log(ILSmax)	<	1.4
log(ILSmax)	=	1.72
log(ILSmax)	=	1.51
log(ILSmax)	<	1.4
log(ILSmax)	=	1.7
log(ILSmax)	=	1.4
log(ILSmax)	=	1.4
log(ILSmax)	=	1.96
log(ILSmax)	=	1.53
log(ILSmax)	<	1.4
log(ILSmax)	<	1.4
log(ILSmax)	<	1.4
log(ILSmax)	<	1.4
log(ILSmax)	<	1.4
log(ILSmax)	<	1.4
log(ILSmax)	=	1.42

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL3232196

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1979
Volume: 22
Issue: 2
First Page: 134
Last Page: 150
DOI: 10.1021/jm00188a005

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
LD10	=	21	mg kg-1
LD10	=	59	mg kg-1
LD10	=	57	mg kg-1
LD10	=	20	mg kg-1
LD10	=	6	mg kg-1
LD10	=	18	mg kg-1
LD10	=	16	mg kg-1
LD10	=	3	mg kg-1
LD10	=	9	mg kg-1
LD10	=	25	mg kg-1
LD10	=	4	mg kg-1
LD10	=	210	mg kg-1
LD10	=	150	mg kg-1
LD10	=	270	mg kg-1
LD10	=	2	mg kg-1
LD10	=	4	mg kg-1
LD10	=	200	mg kg-1
LD10	=	300	mg kg-1
LD10	=	4	mg kg-1
LD10	=	6	mg kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3232195

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1979
Volume: 22
Issue: 2
First Page: 134
Last Page: 150
DOI: 10.1021/jm00188a005

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.3	C50	=	0.3	uM
0.3	C50	=	0.3	uM
0.16	C50	=	0.16	uM
61	C50	=	61	uM
0.3	C50	=	0.3	uM
0.63	C50	=	0.63	uM
0.3	C50	=	0.3	uM
0.48	C50	=	0.48	uM
1.14	C50	=	1.14	uM
0.84	C50	=	0.84	uM
0.84	C50	=	0.84	uM
7.8	C50	=	7.8	uM
6.9	C50	=	6.9	uM
1.5	C50	=	1.5	uM
6.8	C50	=	6.8	uM
0.9	C50	=	0.9	uM
2.2	C50	=	2.2	uM
0.42	C50	=	0.42	uM
0.48	C50	=	0.48	uM
0.44	C50	=	0.44	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3232198

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1979
Volume: 22
Issue: 2
First Page: 134
Last Page: 150
DOI: 10.1021/jm00188a005

Standard Type	Standard Relation	Standard Value
Rm	=	0.3
Rm	=	0.67
Rm	=	0.92
Rm	=	0.8
Rm	=	-0.01
Rm	=	0.6
Rm	=	0.85
Rm	=	-0.2
Rm	=	0.11
Rm	=	0.9
Rm	=	-0.11
Rm	=	0.41
Rm	=	0.78
Rm	=	0.85
Rm	=	1.25
Rm	=	0.02
Rm	=	0.59
Rm	=	1.1
Rm	=	-0.4
Rm	=	-0.15

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3232200

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1979
Volume: 22
Issue: 2
First Page: 134
Last Page: 150
DOI: 10.1021/jm00188a005

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.28	C50	=	0.28	uM
0.18	C50	=	0.18	uM
0.35	C50	=	0.35	uM
0.16	C50	=	0.16	uM
63	C50	=	63	uM
0.22	C50	=	0.22	uM
0.5	C50	=	0.5	uM
0.13	C50	=	0.13	uM
0.22	C50	=	0.22	uM
0.77	C50	=	0.77	uM
0.44	C50	=	0.44	uM
0.72	C50	=	0.72	uM
8.1	C50	=	8.1	uM
5.4	C50	=	5.4	uM
1.1	C50	=	1.1	uM
5.3	C50	=	5.3	uM
1.2	C50	=	1.2	uM
2.3	C50	=	2.3	uM
0.41	C50	=	0.41	uM
0.4	C50	=	0.4	uM

60172-01-2 靶点实验数据