Copper??Catalyzed Si B Bond Activation in Branched??Selective Allylic Substitution of Linear Allylic Chlorides

DJ Vyas, M Oestreich

Index: Vyas, Devendra J.; Oestreich, Martin Angewandte Chemie - International Edition, 2010 , vol. 49, # 45 p. 8513 - 8515

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Citation Number: 52

Abstract

The transmetalation of interelement linkages with CuIÀ Oalkyl complexes provides a facile entry into nucleophilic main group element/copper (I) compounds. An intriguing sbond metathesis is believed to be the activating step, thus building a conceptual bridge between the emerging areas of CuIÀH,[1a] CuIÀB,[1b] and CuIÀSi [1c] chemistry (I–III; Figure 1). Both conjugate addition [2–4] and allylic or propargylic substitutions [5–7] with these reagents ...