Sodium borohydride in reductive amination reactions

…, YD Markovich, IP Ivashev, AA Zhirov, AF Eleev…

Index: Panfilov; Markovich; Ivashev; Zhirov; Eleev; Kurochkin; Kirsanov; Nazarov Pharmaceutical Chemistry Journal, 2000 , vol. 34, # 2 p. 76 - 78

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Citation Number: 6

Abstract

Among a variety of methods developed for the synthesis of substituted amines from carbonyl-containing compounds, a promising approach is that based on the reductive amination (hydroamination) reaction. The set of available complex borohydrides used in this process is restricted to several compounds such as sodium cyanoborohydride and sodium or lithium triacetoxyborohydrides [1 - 3]. It was es- tablished that reactions involving these compounds include several ...