A New and Facile Synthesis of Quinazoline-2, 4 (1 H, 3 H)-diones

L Jiarong, C Xian, S Daxin, M Shuling, L Qing, Z Qi…

Index: Jiarong, Li; Xian, Chen; Daxin, Shi; Shuling, Ma; Qing, Li; Qi, Zhang; Jianhong, Tang Organic Letters, 2009 , vol. 11, # 6 p. 1193 - 1196

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Citation Number: 65

Abstract

In recent decades, quinazoline-2,4(1H,3H)-diones have drawn the attention of chemists and medicinal chemists because of their various biological activities for use as α-adrenergic receptor antagonists,(1) anticonvulsants,(2) antibacterial,(3) psychosedative,(4) antihypertensive,(5) or hypotensive compounds, or inhibitors of puromycin-sensitive aminopeptidase.(6) Quinazoline-2,4(1H,3H)-diones are also useful synthetic materials in heterocyclic ...