β-Peptides as catalysts: poly-β-leucine as a catalyst for the Julia–Colonna asymmetric epoxidation of enones

…, KH Drauz, SM Roberts, J Skidmore…

Index: Coffey; Drauz; Roberts; Skidmore; Smith Chemical communications (Cambridge, England), 2001 , # 22 p. 2330 - 2331

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Citation Number: 26

Abstract

Peptides, generated from α-amino acids, can adopt a number of stable conformations such as the α-helix and β-sheet. In combination these secondary structural units allow a protein to adopt a defined tertiary structure, which can lead to catalytic behaviour. Recent work by Seebach, 1 Gellman 2 and others, 3 as well as earlier studies, 4 has shown that peptides generated from β-amino acids (so called β-peptides) show similar secondary structural characteristics to ...