A New Family of Tunable Indolylphosphine Ligands by One-Pot Assembly and Their Applications in Suzuki− Miyaura Coupling of Aryl Chlorides

…, CC Yeung, CP Lau, FY Kwong

Index: Chau, Ming So; Chung, Chiu Yeung; Chak, Po Lau; Fuk, Yee Kwong Journal of Organic Chemistry, 2008 , vol. 73, # 19 p. 7803 - 7806

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Citation Number: 69

Abstract

This study describes a new class of indolylphosphine ligands, which can be easily accessed by a simple one-pot assembly from commercially available indoles, acid chlorides, and chlorophosphines. A combination of these three starting materials provides a high diversification of the ligand structure. The application of this ligand array in palladiumcatalyzed Suzuki-Miyaura coupling reaction of aryl chlorides with arylboronic ...