Oxidative dimerization of primary alcohols to esters catalyzed by iridium complexes

A Izumi, Y Obora, S Sakaguchi, Y Ishii

Index: Izumi, Aki; Obora, Yasushi; Sakaguchi, Satoshi; Ishii, Yasutaka Tetrahedron Letters, 2006 , vol. 47, # 52 p. 9199 - 9201

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Citation Number: 44

Abstract

Primary alcohols undergo efficiently oxidative dimerization by iridium complexes under air without any solvent to form esters in fair to good yields. For instance, the reaction of 1- dodecanol in the presence of [IrCl (coe) 2] 2 (3mol%) at 95° C for 15h produced dodecyl dodecanoate in 91% isolated yield. This is the first successful Ir-catalyzed oxidative dimerization of primary alcohols to esters using air as an oxidant. Various primary ...