Improved synthesis of 3, 4-dihydro-2, 6-dimethyl-4-oxoquinazoline

S Chen, J Lin, B Qin

Index: Chen, Shiyan; Lin, Jimao; Qin, Bingjie Organic Preparations and Procedures International, 2004 , vol. 36, # 3 p. 277 - 279

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Abstract

oxidized products obtained above, acetic acid anhydride (4.07 g, 0.04 mol) and petroleum ether (60-9o" c)(1 3.8 mL) were heated to reflux for about 3 hrs and cooled to 20- and ammonium acetate (6.9 g, 0.09 mol) was added. The mixture was distilled under atmospheric pressure until approximately 8 mL of petroleum ether (60-90 C) had distilled. Acetic acid (20 mL) was then added and the distillation was continued until approximately ...