The oxidation of a steroidal bromohydrin revisited.

B H Jennings, L M Yelle

Index: Steroids 37(1) , 7-22, (1981)

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Abstract

A comparative study was made of the reactions of 5-bromo-3 beta, 6 beta-dihydroxy-5 alpha-androstan-17-one 3-acetate (1) with lead tetraacetate alone and in the presence of iodine in both high intensity visible light and in total darkness using a variety of solvents. Markedly different product profiles were obtained under the different reaction conditions, making our results of both practical importance and theoretical interest.