Synthesis, characterization and biological evaluation of some 16E-arylidene androstane derivatives as potential anticancer agents

Hao Guo, Haotian Wu, Jin Yang, Yuling Xiao, Hans-Josef Altenbach, Guofu Qiu, Hao Hu, Zhongyuan Wu, Xianran He, Dingshan Zhou, Xianming Hu, Hao Guo, Haotian Wu, Jin Yang, Yuling Xiao, Hans-Josef Altenbach, Guofu Qiu, Hao Hu, Zhongyuan Wu, Xianran He, Dingshan Zhou, Xianming Hu

Index: Steroids 76(7) , 709-23, (2011)

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Abstract

Graphical abstract . A series of new 16E-arylidene androstane derivatives were synthesized and evaluated for their anticancer activities against four cancer cell lines SW480, A549, HepG2 and HeLa in vitro.