Whole genome sequence of the rifamycin B-producing strain Amycolatopsis mediterranei S699.

Mansi Verma, Jaspreet Kaur, Mukesh Kumar, Kirti Kumari, Anjali Saxena, Shailly Anand, Aeshna Nigam, Vydianathan Ravi, Saurabh Raghuvanshi, Paramjit Khurana, Akhilesh K Tyagi, Jitendra P Khurana, Rup Lal

Index: J. Bacteriol. 193(19) , 5562-3, (2011)

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Abstract

Amycolatopsis mediterranei S699 is an actinomycete that produces an important antibiotic, rifamycin B. Semisynthetic derivatives of rifamycin B are used for the treatment of tuberculosis, leprosy, and AIDS-related mycobacterial infections. Here, we report the complete genome sequence (10.2 Mb) of A. mediterranei S699, with 9,575 predicted coding sequences.