The MPEG monophosphate ester: synthesis and characterization.

Stanislaw Penczek, Krzysztof Kaluzynski, Blazej Wisniewski, Julia Pretula, Ryszard Szymanski, Grzegorz Lapienis

Index: J. Biomater. Sci. Polym. Ed. 20(14) , 2103-16, (2009)

Full Text: HTML

Abstract

Methods of preparation of the phosphoric ester of monomethyl ether of poly(ethylene glycol) (MPEG-P) from MPEG (M(n) = 550 and 2000) and phosphoric acid (P), or its derivatives - pyrophosphoric acid (PY), polyphosphoric acid (PP) and POCl(3)- are described and compared. MPEG-P was isolated in a pure state (no detectable impurities) and characterized.