Amy C Young, Larissa I Velez, Kurt C Kleinschmidt
Index: Resuscitation 80(5) , 591-3, (2009)
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We report the first case of sustained-release verapamil toxicity treated with Intralipid fat emulsion (IFE). Toxicity was confirmed by elevated serial serum verapamil and metabolite, norverapamil, levels. Most previously reported cases of IFE therapy involve local anaesthetic toxicity and cardiac arrest. Our patient was in shock despite standard therapy. No adverse events were noted and the patient fully recovered.
| Structure | Name/CAS No. | Molecular Formula | Articles |
|---|---|---|---|
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Norverapamil hydrochloride
CAS:67812-42-4 |
C26H37ClN2O4 |
|
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Application of permeability-limited physiologically-based ph...
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Comparative cardiovascular actions of verapamil and its majo...
1978-04-01 [Cardiovasc. Res. 12 , 247-254, (1978)] |
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The pharmacology of verapamil. V. Tissue distribution of ver...
1983-01-01 [Pharmacology 27 , 1-8, (1983)] |
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