A new "turn-on" chemodosimeter for Hg2+: ICT fluorophore formation via Hg(2+)-induced carbaldehyde recovery from 1,3-dithiane.

Yuncong Chen, Chengcheng Zhu, Zhenghao Yang, Jing Li, Yang Jiao, Weijiang He, Junjie Chen, Zijian Guo

Index: Chem. Commun. (Camb.) 48(42) , 5094-6, (2012)

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Abstract

A novel sensitive and specific Hg(2+) chemodosimeter, derived from 1',3'-dithiane-substituted 2,1,3-benzoxadiazole, displays "turn-on" fluorescent and colorimetric responses via an Hg(2+)-triggered aldehyde recovery reaction. Its potential to monitor Hg(2+) in living organisms has been demonstrated using zebrafish larvae.This journal is © The Royal Society of Chemistry 2012