New beyerane and isopimarane diterpenoids from Rhizophora mucronata.

Ammanamanchi S R Anjaneyulu, Vallurupalli Anjaneyulu, Vadali Lakshmana Rao

Index: J. Asian Nat. Prod. Res. 4(1) , 53-61, (2002)

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Abstract

Chemical examination of the ethyl acetate extract of the roots of Rhizophora mucronata collected from Mangalore Coast resulted in the isolation of three more new diterpenoids, rhizophorins C-E (1-3) in addition to the two, rhizophorin A, (6R,11S,13S)-6,11,13-trihydroxy-2,3-seco-14-labden-2,8-olid-3-oic acid, and rhizophorin B, ent-3beta,20-epoxy-3alpha,18-dihydroxy-15-beyerene, recently reported. The structures of the new diterpenoids have been elucidated by a study of their physical and spectral data as 17-hydroxybeyer-15-en-3-one (1), 3beta,17-diacetoxy-15-beyeren-2-one (2) and 3beta,6alpha-diacetoxy-8(14),15-isopimaradien-2-one (3).