3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chloro-3 -fluorophenoxy}-5-chlorobenzonitrile
Modify Date: 2026-04-14 22:02:10
![3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chloro-3 -fluorophenoxy}-5-chlorobenzonitrile Structure](http://hg.y866.cn/chemical/lib/image/caspic/217/920035-90-1.png)
3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chloro-3 -fluorophenoxy}-5-chlorobenzonitrile structure
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Common Name | 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chloro-3 -fluorophenoxy}-5-chlorobenzonitrile | ||
|---|---|---|---|---|
| CAS Number | 920035-90-1 | Molecular Weight | 444.24600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H12Cl2FN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
| Name | 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chloro-3 -fluorophenoxy}-5-chlorobenzonitrile |
|---|
| Molecular Formula | C20H12Cl2FN5O2 |
|---|---|
| Molecular Weight | 444.24600 |
| Exact Mass | 443.03500 |
| PSA | 110.57000 |
| LogP | 5.15908 |
| InChIKey | JDKMJELQOXOOJD-UHFFFAOYSA-N |
| SMILES | N#Cc1cc(Cl)cc(Oc2cc(OCc3[nH]nc4nc(N)ccc34)cc(F)c2Cl)c1 |
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Name: Half life in Beagle dog at 0.5 mg/kg, iv
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL1037197
|
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Name: Oral bioavailability in Beagle dog at 1 mg/kg
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL1037198
|
|
Name: Plasma concentration in rat at 10 mg/kg, po after 24 hrs
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL1038945
|
|
Name: Volume of distribution in Beagle dog at 0.5 mg/kg, iv
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL1037195
|
|
Name: Plasma concentration in rat at 100 mg/kg, po after 24 hrs
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL1038946
|
|
Name: Cardiotoxicity in conscious cardiovascular dog assessed as electrocardiogram at 10 mg...
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL1038943
|
|
Name: Oral bioavailability in Sprague-Dawley rat at 10 mg/kg
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL1037193
|
|
Name: Genotoxicity in Salmonella Typhimurium strain FU100 assessed as increase in mutants b...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1038944
|
|
Name: Clearance in Beagle dog at 0.5 mg/kg, iv
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL1037194
|
|
Name: Cardiotoxicity in conscious cardiovascular dog assessed as mean arterial pressure at ...
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL1038941
|
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