| Identification | Back Directory | [Name]
PROCYANIDINB533DIOGALLATE | [CAS]
106533-60-2 | [Synonyms]
PROCYANIDINB533DIOGALLATE
ProcyanidinB-533'-di-O-gallate/ProcyanidinB533-di-O-gallate | [Molecular Formula]
C44H34O20 | [MOL File]
106533-60-2.mol | [Molecular Weight]
882.729 |
| Hazard Information | Back Directory | [Uses]
Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC50 of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity[1]. | [Definition]
ChEBI: (2R,3R)-2-(3,4-Dihydroxyphenyl)-6-[(2R,3R,4S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-4-yl]-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate is a flavonoid oligomer. | [References]
[1] Abe I, et al. Galloyl esters from rhubarb are potent inhibitors of squalene epoxidase, a key enzyme in cholesterol biosynthesis. Planta Med. 2000 Dec;66(8):753-6. DOI:10.1055/s-2000-9781 |
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