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15923-78-1

15923-78-1 Structure

15923-78-1 Structure
IdentificationBack Directory
[Name]

1,2,3,4,5,6-HEXAHYDRO-6-METHYL-AZEPINO[4,5-B]INDOLE HYDROCHLORIDE
[CAS]

15923-78-1
[Synonyms]

PNU 22394 HYDROCHLORIDE
Azepino[4,5-b]indole, 1,2,3,4,5,6-hexahydro-6-methyl-
1,2,3,4,5,6-HEXAHYDRO-6-METHYL-AZEPINO[4,5-B]INDOLE HYDROCHLORIDE
[Molecular Formula]

C13H16N2
[MDL Number]

MFCD01665206
[MOL File]

15923-78-1.mol
[Molecular Weight]

200.28
Chemical PropertiesBack Directory
[Boiling point ]

383.0±32.0 °C(Predicted)
[density ]

1.17±0.1 g/cm3(Predicted)
[storage temp. ]

Desiccate at +4°C
[pka]

10.73±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

PNU 22394 is a potent SR-2C agonist and partial SR-2A/SR-2B agonist. Central nervous system sedative. A tryptamine derivative which has hyperthermic effects.
[Biological Activity]

Potent 5-HT 2C agonist and partial 5-HT 2A /5-HT 2B agonist. Non-selective between 5-HT 2 receptor subtypes (K i values are 18, 18 and 66 nM for human recombinant 5-HT 2C , 5-HT 2A and 5-HT 2B receptors respectively). Reduces food intake in rats following subcutaneous administration and displays anorexigenic effects in humans.
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