| Identification | Back Directory | [Name]
IL-15-IN-1 | [CAS]
1831830-20-6 | [Synonyms]
IL-15-IN-1
Benzoic acid, 3-[[8-[[5-[(3,4-dihydro-3-methyl-4-oxo-1-phthalazinyl)methyl]-4-methyl-4H-1,2,4-triazol-3-yl]thio]-1-oxooctyl]amino]-, ethyl ester | [Molecular Formula]
C30H36N6O4S | [MDL Number]
MFCD31813614 | [MOL File]
1831830-20-6.mol | [Molecular Weight]
576.71 |
| Chemical Properties | Back Directory | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (216.75 mM; Need ultrasonic) | [form ]
Solid | [pka]
14.63±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
IL-15-IN-1 (compound 76) is a potent and selective Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells with an IC50 of 0.8 μM[1]. | [IC 50]
IL-15: 0.8 μM (IC50) | [References]
[1] Quéméner A, et al. Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization. J Med Chem. 2017 Jul 27;60(14):6249-6272. DOI:10.1021/acs.jmedchem.7b00485 |
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| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 |
| Website: |
http://www.weikeqi-biotech.com/ |
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