| Identification | Back Directory | [Name]
Myriceric acid B | [CAS]
55497-79-5 | [Synonyms]
Myriceric acid B
Wax fruit myric acid B
Olean-12-en-28-oic acid,27-[[(2E)-3-(3,4-dihydroxyphenyl)-1- oxo-2-propenyl]oxy]-3-hydroxy-,(3a)-
Olean-12-en-28-oic acid, 27-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3-hydroxy-, (3β)- | [Molecular Formula]
C39H54O7 | [MDL Number]
MFCD20274875 | [MOL File]
55497-79-5.mol | [Molecular Weight]
634.84 |
| Hazard Information | Back Directory | [Uses]
Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41. Myriceric acid B is an antitumor agent[1][2]. | [IC 50]
HIV-1: 8.3±0.2 μg/mL (IC50, infection of HIV-1 Env pseudovirus) | [References]
[1] Eom HJ, et al. Cytotoxic Triterpenoids from the Barks of Betula platyphylla var. japonica. Chem Biodivers. 2017 Apr;14(4). DOI:10.1002/cbdv.201600400
[2] Xia C, et al. The anti-HIV-1 entrance activity and mechanism of action of myriceric acid B from Rhoiptelea chiliantha Diels et Hand-Mazz. Chinese Pharmacological Bulletin, 2010: 447-452. |
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