| Identification | Back Directory | [Name]
(12R,15S)-12,15-Epoxy-15,20-dihydro-16a-homo-21-norsenecionan-11,16a-dione | [CAS]
62018-78-4 | [Synonyms]
Retroisosenine
(12R,15S)-12,15-Epoxy-15,20-dihydro-16a-homo-21-norsenecionan-11,16a-dione
4,7-Epoxy-2H-[1,6]dioxacyclotridecino[2,3,4-gh]pyrrolizine-2,8(3H)-dione, 4,5,6,7,10,12,14,15,15a,15b-decahydro-4,6,7-trimethyl-, (4R,6R,7S,15aR,15bR)- | [Molecular Formula]
C18H25NO5 | [MOL File]
62018-78-4.mol | [Molecular Weight]
335.39 |
| Chemical Properties | Back Directory | [Occurrence]
A pyrrolizidine alkaloid, retroisosenine occurs in the basic extract of Senecio nemorensis. It
crystallizes as colourless rods from EtOH and is dextrorotatory with a specific rotation of
[α]D24 + 118°(c 0.69, CHCl3).The ultraviolet spectrum in EtOH consists of a single absorption maximum at 220nm. |
| Hazard Information | Back Directory | [Uses]
Retroisosenine is a pyrrolizidine alkaloid isolated from the plant of the genus Senecio. Its specific mechanism of activity and application details are not described in detail from the existing information. | [References]
[1] Iodanthine, a pyrrolizidine alkaloid from senecio iodanthus and senecio bracteatus |
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