ChemicalBook >> CAS DataBase List >>Insulin-like Growth Factor-1 Receptor Inhibitor
Insulin-like Growth Factor-1 Receptor Inhibitor
- CAS No.
- 468740-43-4
- Chemical Name:
- Insulin-like Growth Factor-1 Receptor Inhibitor
- Synonyms
- CS-469;CS-0117;HY-10262;BMS-536924;BMS-536924, >=98%;BMS-536924 (CS0117;BMS 536924;BMS536924;BMS-536924 >=98% (HPLC);BMS-536924, 10 mM in DMSO;BMS-536924(HY-10262, CS-0117)
- CBNumber:
- CB22510062
- Molecular Formula:
- C25H26ClN5O3
- Molecular Weight:
- 479.96
- MDL Number:
- MFCD14635360
- MOL File:
- 468740-43-4.mol
- MSDS File:
- SDS
Last updated:2025-04-17 18:22:24
| Product description | Number | Pack Size | Price |
| BMS-536924 ≥98% | 14666 | 1mg | $49 |
| BMS-536924 ≥98% | 14666 | 5mg | $190 |
| BMS-536924 ≥98% | 14666 | 10mg | $286 |
| BMS-536924 ≥98% | 14666 | 25mg | $651 |
| BMS536924 ≥98%(HPLC) | 4774 | 10 | $292 |
| More product size | |||
| Melting point | >206°C (dec.) |
|---|---|
| Density | 1.44 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly) |
| form | Solid |
| pka | 10.40±0.10(Predicted) |
| color | Light Yellow to Yellow |
| CAS DataBase Reference | 468740-43-4 |
| FDA UNII | 40E3AZG1MX |
Insulin-like Growth Factor-1 Receptor Inhibitor price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14666 | BMS-536924 ≥98% | 468740-43-4 | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 14666 | BMS-536924 ≥98% | 468740-43-4 | 5mg | $190 | 2024-03-01 | Buy |
| Cayman Chemical | 14666 | BMS-536924 ≥98% | 468740-43-4 | 10mg | $286 | 2024-03-01 | Buy |
| Cayman Chemical | 14666 | BMS-536924 ≥98% | 468740-43-4 | 25mg | $651 | 2024-03-01 | Buy |
| Tocris | 4774 | BMS536924 ≥98%(HPLC) | 468740-43-4 | 10 | $292 | 2021-12-16 | Buy |
Insulin-like Growth Factor-1 Receptor Inhibitor Chemical Properties,Uses,Production
Uses
BMS 536924 is an inhibitor of insulin-like growth factor receptor (IGF1R) kinase and insulin receptor. BMS 536924 was reported to have antitumor activity.
Definition
ChEBI: 4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-[4-methyl-6-(4-morpholinyl)-1,3-dihydrobenzimidazol-2-ylidene]-2-pyridinone is a member of benzimidazoles.
in vivo
BMS-536924 (100 mg/kg; gavage; daily; for 35 days) causes regression of xenografts in vivo and an average reduction of 76% tumor volume after 2 weeks[2].
| Animal Model: | Athymic nude mice with CD8-IGF-IRMCF10A cells[2] |
| Dosage: | 100 mg/kg |
| Administration: | Gavage; daily; for 35 days |
| Result: | Caused an average reduction of 76% tumor volume after 2 weeks. |
storage
Store at -20°C
Insulin-like Growth Factor-1 Receptor Inhibitor Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 133)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 19282 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39042 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
View Lastest Price from Insulin-like Growth Factor-1 Receptor Inhibitor manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | Insulin-like Growth Factor-1 Receptor Inhibitor
468740-43-4
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co | |
|
|
2020-01-13 | Insulin-like Growth Factor-1 Receptor Inhibitor
468740-43-4
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- Insulin-like Growth Factor-1 Receptor Inhibitor
468740-43-4
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co
-
- Insulin-like Growth Factor-1 Receptor Inhibitor
468740-43-4
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co
468740-43-4(Insulin-like Growth Factor-1 Receptor Inhibitor)Related Search:
4-[[(2S)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-3-[7-methyl-5-(4-morpholinyl)-1H-benzimidazol-2-yl]-2(1H)-pyridinone
CS-469
BMS 536924;BMS536924
BMS-536924
Insulin-like Growth Factor-1 Receptor Inhibitor
4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-[4-methyl-6-(4-morpholinyl)-1H-benzimidazol-2-yl]- 2(1H)-pyridinone
CS-0117
HY-10262
BMS-536924
Insulin-like Growth Factor-1 Receptor Inhibitor
BMS-536924, >=98%
4-[[(2S)-2-(3-Chlorophenyl)-2-hydroxyethyl]aMino]-3-[7-Methyl-5-(4-Morpholinyl)-1H-benziMidazol-2-yl]-2(1H)-pyridinone BMS-536924
(S)-4-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one
BMS-536924(HY-10262, CS-0117)
2(1H)-Pyridinone, 4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-[7-methyl-5-(4-morpholinyl)-1H-benzimidazol-2-yl]-
BMS-536924 >=98% (HPLC)
Insulin-like Growth Factor-1 Receptor Inhibitor USP/EP/BP
(S)-4-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one
BMS-536924 (CS0117
Insulin-like Growth Factor-1 Receptor Inhibito
BMS-536924, 10 mM in DMSO
468740-43-4
C25H26ClN5O3
Inhibitors
