ChemicalBook >> CAS DataBase List >>E3 Ligand-Linker Conjugate 6

E3 Ligand-Linker Conjugate 6

CAS No.
2022182-57-4
Chemical Name:
E3 Ligand-Linker Conjugate 6
Synonyms
Pomadomide impurity 26;E3 Ligand-Linker Conjugate 6;N-(3-aminopropyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide;Acetamide, N-(3-aminopropyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
CBNumber:
CB34667860
Molecular Formula:
C18H20N4O6
Molecular Weight:
388.37
MDL Number:
MFCD31812749
MOL File:
2022182-57-4.mol
Last updated:2025-04-18 09:52:07
Product description Number Pack Size Price
E3Ligand-LinkerConjugate6 >98% DC11572 100mg $600
E3Ligand-LinkerConjugate6 >98% DC11572 1g $1900

E3 Ligand-Linker Conjugate 6 Properties

Boiling point 755.0±60.0 °C(Predicted)
Density 1.431±0.06 g/cm3(Predicted)
pka 10.68±0.40(Predicted)

SAFETY

Risk and Safety Statements

E3 Ligand-Linker Conjugate 6 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
DC Chemicals DC11572 E3Ligand-LinkerConjugate6 >98% 2022182-57-4 100mg $600 2021-12-16 Buy
DC Chemicals DC11572 E3Ligand-LinkerConjugate6 >98% 2022182-57-4 1g $1900 2021-12-16 Buy
Product number Packaging Price Buy
DC11572 100mg $600 Buy
DC11572 1g $1900 Buy

E3 Ligand-Linker Conjugate 6 Chemical Properties,Uses,Production

Uses

Thalidomide-O-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

IC 50

Cereblon

References

[1] Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262. DOI:10.1016/j.bmcl.2016.09.048

E3 Ligand-Linker Conjugate 6 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 Ligand-Linker Conjugate 6 Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanxi Tihondan Pharmaceutical Technology Co., Ltd
+8618235132063 sales@tihondan.com China 3767 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3869 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1625 58
Shandong Territorial sea Biological Technology Co., LTD 15092083467 18660263263@163.com China 2870 58
Molcoo Chemicals Inc. 18576690171 3001025734@qq.com China 8892 58
Shenzhen Roark Pharma-Tec Co., Ltd. 13128912434 2880126944@qq.com China 3099 58
Abosyn 0512-69561983 13914027025 he_qf@medinoah.com China 3001 58
Huanuo Pharmaceutical Technology (Guangxi) Co., Ltd 13005928603 211017228@qq.com China 10000 58
Hubei Moco Chemical Co., Ltd. 18627753421; 18627756402 3001051413@qq.com China 20317 58
E3 Ligand-Linker Conjugate 6 Acetamide, N-(3-aminopropyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- N-(3-aminopropyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide Pomadomide impurity 26 2022182-57-4