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ELA-11 (human)

CAS No.
1784687-32-6
Chemical Name:
ELA-11 (human)
Synonyms
ELA-11 (human);L-Proline, L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-
CBNumber:
CB44902715
Molecular Formula:
C58H90N16O13S2
Molecular Weight:
1283.56
MDL Number:
MOL File:
1784687-32-6.mol
Last updated:2025-06-18 16:39:24

ELA-11 (human) Properties

Density 1.47±0.1 g/cm3(Predicted)
form Solid
pka 3.43±0.20(Predicted)
color White to off-white
Sequence Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro

ELA-11 (human) Chemical Properties,Uses,Production

Uses

ELA-11(human), a peptide, is a full agonist of human apelin receptor, with a pKi of 7.85. ELA-11(human) completely inhibits Forskolin-induced cAMP production and stimulates β-arrestin recruitment[1].

References

[1] Yang P, et, al. Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension. Circulation. 2017 Mar 21;135(12):1160-1173. DOI:10.1161/CIRCULATIONAHA.116.023218

ELA-11 (human) Preparation Products And Raw materials

Raw materials

Preparation Products

ELA-11 (human) Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10405 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599 info@molchanges.com China 5218 58
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 18101056239 3193328036@qq.com China 29759 68
Chengdu Youngshe Chemical Co., Ltd. +86-17380623303 Caroline@youngshechem.com China 4802 58
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 Eric@peptidego.com China 7408 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
Hangzhou Go Top Peptide Biotech 15397062932 sales1@gotopbio.com China 2928 58
Shaoxing Junyu Biotechnology Co., LTD 0571-0571-88211921 19105816207 sales4@gotopbio.com China 5144 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 0571-87213919 17306812703 3007955328@qq.com China 6979 58
ELA-11 (human) L-Proline, L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl- 1784687-32-6