ChemicalBook >> CAS DataBase List >>(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE

CAS No.
112811-70-8
Chemical Name:
(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE
Synonyms
Moxifloxacin Impurity Ⅷ;Azilsartan medoxomil impurity266;Moxifloxacin Intermediate Impurity 2;Moxifloxacin Intermediate Impurity 2 Control;Ethyl 2-(2,4,5-trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylate;ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate;Ethyl(Z)-3-(Cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate;(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE;(E)-ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate;2-(2,4,5-Trifluoro-3-Methoxybenzoyl)-3-cyclopropylaMinoacrylic Acid Ethyl Ester
CBNumber:
CB52468409
Molecular Formula:
C16H16F3NO4
Molecular Weight:
343.3
MDL Number:
MFCD11973763
MOL File:
112811-70-8.mol
MSDS File:
SDS
Last updated:2025-07-04 15:10:56
Product description Number Pack Size Price
2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylicAcidEthylEster T790730 500mg $1320
2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylicAcidEthylEster 49055 500mg $2200
More product size

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Properties

Boiling point 463.2±45.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
pka 2.70±0.70(Predicted)
InChI InChI=1S/C16H16F3NO4/c1-3-24-16(22)10(7-20-8-4-5-8)14(21)9-6-11(17)13(19)15(23-2)12(9)18/h6-8,20H,3-5H2,1-2H3/b10-7-
InChIKey HVJXUGXNDLCTGC-YFHOEESVSA-N
SMILES C(=C/NC1CC1)(\C(C1C(F)=C(OC)C(F)=C(F)C=1)=O)/C(=O)OCC

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T790730 2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylicAcidEthylEster 112811-70-8 500mg $1320 2021-12-16 Buy
Medical Isotopes, Inc. 49055 2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylicAcidEthylEster 112811-70-8 500mg $2200 2021-12-16 Buy
Product number Packaging Price Buy
T790730 500mg $1320 Buy
49055 500mg $2200 Buy

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Chemical Properties,Uses,Production

Uses

2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylic Acid Ethyl Ester is used in the preparation Gatifloxacin (G250000) and key intermediates for the synthesis third-generation fluoroquinolone antibiotics.

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE 2-(2,4,5-Trifluoro-3-Methoxybenzoyl)-3-cyclopropylaMinoacrylic Acid Ethyl Ester Ethyl 2-(2,4,5-trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylate (E)-ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate Moxifloxacin Impurity Ⅷ 3-(cyclopropylamino)-2-[oxo-(2,4,5-trifluoro-3-methoxyphenyl)methyl]-2-propenoic acid ethyl ester Moxifloxacin Intermediate Impurity 2 Control Moxifloxacin Intermediate Impurity 2 Benzenepropanoic acid, α-[(cyclopropylamino)methylene]-2,4,5-trifluoro-3-methoxy-β-oxo-, ethyl ester ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate Benzenepropanoic acid, α-[(cyclopropylamino)methylene]-2,4,5-trifluoro-3-methoxy-β-oxo-, ethyl ester (9CI, ACI) Azilsartan medoxomil impurity266 Ethyl(Z)-3-(Cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate 112811-70-8 Amines Aromatics Intermediates