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3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine structure

CAS No.: 1022150-12-4

Chemical Name:: 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine

Synonyms: (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;ibrutinib N-1;3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride;IBT6A ，E2250;Ilutinib impurity 18;IBT6A, 10 mM in DMSO;Ibrutinib Impurity 18;4-d]pyriMidin-4-ylaMine;Ibrutinib intermediate 1

CBNumber:: CB52623905

Molecular Formula:: C22H22N6O

Molecular Weight:: 386.45

MDL Number:: MFCD20482137

MOL File:: 1022150-12-4.mol

MSDS File:: SDS

Last updated:2025-12-23 21:30:31

Product description	Number	Pack Size	Price
(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	P318770	10g	$845
(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	P318770	5g	$545
3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 97%	132822	5g	$864
3-(4-PHENOXY-PHENYL)-1-PIPERIDIN-3-YL-1H-PYRAZOLO-[3,4-D]PYRIMIDIN-4-YLAMINE 95.00%	CHM0292889	5G	$1246.25
IBT6A 99.47%	CS-2435	50mg	$1800
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3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Properties

Melting point	133-136oC
Boiling point	626.3±55.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	9.00±0.10(Predicted)
form	Solid
color	White to Pale Yellow
optical activity	-9.6828°(C=0.5249g/100ml MEOH)
InChIKey	GPSQYTDPBDNDGI-MRXNPFEDSA-N
SMILES	C1=NC(N)=C2C(C3=CC=C(OC4=CC=CC=C4)C=C3)=NN([C@@H]3CCCNC3)C2=N1
FDA UNII	NR6GN4MC2R

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	P318770	(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	1022150-12-4	10g	$845	2021-12-16	Buy
TRC	P318770	(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	1022150-12-4	5g	$545	2021-12-16	Buy
Matrix Scientific	132822	3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 97%	1022150-12-4	5g	$864	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0292889	3-(4-PHENOXY-PHENYL)-1-PIPERIDIN-3-YL-1H-PYRAZOLO-[3,4-D]PYRIMIDIN-4-YLAMINE 95.00%	1022150-12-4	5G	$1246.25	2021-12-16	Buy
ChemScene	CS-2435	IBT6A 99.47%	1022150-12-4	50mg	$1800	2021-12-16	Buy

Product number	Packaging	Price	Buy
P318770	10g	$845	Buy
P318770	5g	$545	Buy
132822	5g	$864	Buy
CHM0292889	5G	$1246.25	Buy
CS-2435	50mg	$1800	Buy

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Chemical Properties,Uses,Production

Description

IBT6A is a Btk kinase inhibitor. This compound is a precurser for the manufacture of ibrutinib.

Uses

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton''s tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives.

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine synthesis

Synthesis of 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine from 3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine and (S)-1-Boc-3-hydroxypiperidine

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Preparation Products And Raw materials

Raw materials

Preparation Products

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Suppliers

Global( 282)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20130	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21604	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
Lianyungang happen teng technology co., LTD	15950718863	wang666xt@163.com	CHINA	295	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29843	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60
Lianyungang happen teng technology co., LTD	58
career henan chemical co	58
Biochempartner	58
Accela ChemBio Inc.	58

View Lastest Price from 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-23	IBT6A 1022150-12-4	US $42.00 / mg		99.88%	10g	TargetMol Chemicals Inc.
2025-12-23	IBT6A 1022150-12-4	US $42.00 / mg		99.88%	10g	TargetMol Chemicals Inc.
2025-12-01	Btk inhibitor 1 R enantiomer 1022150-12-4	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

IBT6A
1022150-12-4
US $42.00 / mg
99.88%
TargetMol Chemicals Inc.

IBT6A
1022150-12-4
US $42.00 / mg
99.88%
TargetMol Chemicals Inc.

Btk inhibitor 1 R enantiomer
1022150-12-4
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Spectrum

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine(1022150-12-4)¹HNMR

1022150-12-4(3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine)Related Search:

Chidamide (S)-Ibrutinib 3-(4-Phenoxyphenyl)-1-(4-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Btk inhibitor 1 (R enantioMer hydrochloride) Ibrutinib Impurity 21

Ibrutinib Impurity 10 Imatinib Impurity 72 (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one 1-[(3R)-3-[4-amino-3-[4-(2,3,4,5,6-pentadeuteriophenoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2,3-dihydroxypropan-1-one Prednicarbate

(R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-3-chloropropan-1-one Clindamycin 4-Phosphate Ambroxol hydrochloride N-Deformyl-N-pivaloyl Orlistat 10-Propargyl-10-deazaaminopterin

Cilastatin Esmolol Impurity 2 HCl (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone

1of4

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine 3-(4-Phenoxy-phenyl)-1-(R)-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Btk inhibitor 1 (R enantioMer) ibrutinib N-1 Ibrutinib intermeidate N-1 3-(4-phenoxyphenyl)-1-(3-piperidyl)pyrazolo[3,4-d]pyriMidin-4-aMine 3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-Pyrazolo[3,4-d]pyrimidin-4-amine Ibrutinib (PCI-32765) Intermediates 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl) (R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (R)-4-Amino-3-(4-phenoxyphenyl)-1-(3-piperidyl)-1H-pyrazolo[3,4-d]pyrimidine 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine(Btk inhibitor 1 R enantiomer) Ibrutinib Impurity 18 (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl) (R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidine-4-amine 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine 1022150-12-4 (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1022150-12-4 3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride (R)-3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine Ibrutinib N-1 (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine (S)-Ibrutinib N-Desacryloyl Impurity (R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1 H- pyrazole [3,4- d] pyrimidine-4-amine Ibrutinib N-Desacryloyl Impurity 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl- 3- (4-phenoxy-phenyl) -1-piperidine-3-yl-1H-pyrazolium [3, 4-D] pyrimidin-4-ylamine Ibrutinib intermediate 1 4-d]pyriMidin-4-ylaMine 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3 (R)-3-(4-Phenoxyphenyl)-1 -（piperidin-3-yl）pyrazolo [3,4-D]pyrimidin-4-ylamine 3-(4-phenoxyphenyl)-1-(3-piperidyl)pyrazolo[3,4-d]pyrimidin-... (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMi TIANFUCHEM--1022150-12-4---3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine 3-(4-phenoxypheny)1-((3R)-3-pipeidinyl)-1H-pyrazolo[3.4-dleyrimidin-4-amine Ilutinib impurity 18 (R) -3- (4-phenoxyphenyl) -1- (piperidin-3-yl) pyrazolo [3,4-D] pyrimidin-4-amine Irupuni N-1 intermediate IBT6A, 10 mM in DMSO Intermediate of Ibrutinib (R)-3-(4-PhenChemicalbookoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine IBT6A ，E2250 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4- (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (Intermediate of Ibrutinib) 1022150-12-4 022150-12-4 Ibrutinib Intermediates