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2-Amino-5-nitrobenzophenone

CAS No.
1775-95-7
Chemical Name:
2-Amino-5-nitrobenzophenone
Synonyms
Ro 7-1999;Ro 7-19990;TIMTEC-BB SBB000821;IFLAB-BB F0266-0701;Nitrazepam Impurity 2;Nitrazepam Impurity B;Ciclopirox Impurity 6;LABOTEST-BB LT00000253;2-Benzoyl-4-nitroaniline;Nitrazepam EP Impurity B
CBNumber:
CB7242568
Molecular Formula:
C13H10N2O3
Molecular Weight:
242.23
MDL Number:
MFCD00007364
MOL File:
1775-95-7.mol
MSDS File:
SDS
Last updated:2025-09-11 22:01:37
Product description Number Pack Size Price
2-Amino-5-nitrobenzophenone ≥98% 211737 25g $39.83
2-Amino-5-nitrobenzophenone ≥98% 211737 100g $79
2-Amino-5-nitrobenzophenone >98.0%(HPLC) A1134 25g $62
2-Amino-5-nitrobenzophenone A618400 10g $135
5-Amino-2-nitrobenzophenone 002415 2.5g $403
More product size

2-Amino-5-nitrobenzophenone Properties

Melting point 166-168 °C (lit.)
Boiling point 385.05°C (rough estimate)
Density 1.2480 (rough estimate)
refractive index 1.5300 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka -2.26±0.36(Predicted)
form Solid
color Beige
Water Solubility 3 mg/L (20 C)
InChI InChI=1S/C13H10N2O3/c14-12-7-6-10(15(17)18)8-11(12)13(16)9-4-2-1-3-5-9/h1-8H,14H2
InChIKey PZPZDEIASIKHPY-UHFFFAOYSA-N
SMILES C(C1=CC([N+]([O-])=O)=CC=C1N)(C1=CC=CC=C1)=O
CAS DataBase Reference 1775-95-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII G2X8PCQ4GY
NIST Chemistry Reference Methanone, (2-amino-5-nitrophenyl)phenyl-(1775-95-7)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-37/39-36
WGK Germany  3
RTECS  PC4935000
HS Code  29223990
NFPA 704
0
2 0

2-Amino-5-nitrobenzophenone price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 211737 2-Amino-5-nitrobenzophenone ≥98% 1775-95-7 25g $39.83 2025-07-31 Buy
Sigma-Aldrich 211737 2-Amino-5-nitrobenzophenone ≥98% 1775-95-7 100g $79 2025-07-31 Buy
TCI Chemical A1134 2-Amino-5-nitrobenzophenone >98.0%(HPLC) 1775-95-7 25g $62 2025-07-31 Buy
TRC A618400 2-Amino-5-nitrobenzophenone 1775-95-7 10g $135 2021-12-16 Buy
Usbiological 002415 5-Amino-2-nitrobenzophenone 1775-95-7 2.5g $403 2021-12-16 Buy
Product number Packaging Price Buy
211737 25g $39.83 Buy
211737 100g $79 Buy
A1134 25g $62 Buy
A618400 10g $135 Buy
002415 2.5g $403 Buy

2-Amino-5-nitrobenzophenone Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

2-Amino-5-nitrobenzophenone was used in the synthesis of [5-(4-nitrophenyl)-2-furyl]acrylic acid substituted benzophenone (anti-malarial agent).

Uses

A metabolite of Nitrazepam

Synthesis Reference(s)

Synthetic Communications, 16, p. 485, 1986 DOI: 10.1080/00397918608057727

General Description

FT-IR and Raman spectra of 2-amino-5-nitrobenzophenone (ANBP) has been reported.

Synthesis

5-Nitroanthranilonitrile

17420-30-3

BENZENESULFINIC ACID SODIUM SALT

873-55-2

2-Amino-5-nitrobenzophenone

1775-95-7

2-Cyano-4-nitroaniline (0.3 mmol), sodium benzenesulfinate (0.6 mmol), palladium acetate (10 mol%), 2,2'-bipyridine (20 mol%), p-nitrobenzenesulfonic acid (10 equiv.), tetrahydrofuran (2 mL), and water (1 mL) were sequentially added to a Schlenk tube under the protection of nitrogen atmosphere. The reaction mixture was stirred vigorously at 80 °C for 48 hours. After completion of the reaction, the mixture was poured into ethyl acetate and washed sequentially with saturated sodium bicarbonate solution (2 x 10 mL) and saturated saline (1 x 10 mL). After the aqueous layer was extracted with ethyl acetate, all organic layers were combined and dried with anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure and the residue was purified by fast column chromatography (eluent: hexane/ethyl acetate) to afford the target product 2-amino-5-nitrobenzophenone.

References

[1] Molecules, 2014, vol. 19, # 5, p. 6439 - 6449

17420-30-3
873-55-2
1775-95-7
Synthesis of 2-Amino-5-nitrobenzophenone from 5-Nitroanthranilonitrile and BENZENESULFINIC ACID SODIUM SALT
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View Lastest Price from 2-Amino-5-nitrobenzophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-5-nitrobenzophenone pictures 2025-09-11 2-Amino-5-nitrobenzophenone
1775-95-7
US $0.00 / removed 99.75% 10g TargetMol Chemicals Inc.
2-Amino-5-nitrobenzophenone pictures 2025-09-11 2-Amino-5-nitrobenzophenone
1775-95-7
US $0.00 / removed 99.75% 10g TargetMol Chemicals Inc.
2-Amino-5-nitrobenzophenone pictures 2025-06-10 2-Amino-5-nitrobenzophenone
1775-95-7
US $29.00-69.00 / mg 99.75% 10g TargetMol Chemicals Inc.
(2-amino-5-nitrophenyl)phenyl-methanon 2-Amino-5-nitrodiphenylmethone 2-Amino-5-nitrodiphenylone 2-Benzoyl-4-nitroaniline 5-Nitro-2-aminobenzophenone Benzophenone, 2-amino-5-nitro- Methanone, (2-amino-5-nitrophenyl)phenyl- Methanone,(2-amino-5-nitrophenyl)phenyl- TIMTEC-BB SBB000821 (2-AMINO-5-NITRO-PHENYL)-PHENYL-METHANONE 2-AMINO-5-NITROBENZOPHENONE LABOTEST-BB LT00000253 IFLAB-BB F0266-0701 2-AMINO-5-NITROBENZOPHENONE, 98+% 2-AMINO-5-NITROBENZOPHENONE (DIAZEPAM) 5-Amino-2-nitrobenzophenone Ro 7-1999 Ro 7-19990 2-AMINO-5-NITROBENZOPHENONE=99.0% Nitrazepam Impurity Ⅰ:2-Amino-5-nitrobenzophenone (5-amino-2-nitrophenyl)-phenylmethanone 2-Amino-5-nitrobenzophenon Nitrazepam Impurity 2 2-Amino-5-nitrobenzophenone > 2-Amino-5-Nitrobenzophenone extrapure, 98% Nitrazepam Impurity B Nitrazepam EP Impurity B Ciclopirox Impurity 6 2-Amino-5-nitrodiphenylmethanone (2-Amino-5-nitrophenyl)phenyl-methanone (2-Amino-5-nitrobenzophenone) 2 mino-5-nitrobenzophenone Nitrazepam Impurity Ⅰ:2-Amino-5-nitrobenzophenone 1775-95-7 1778-95-7 C13H10N203 Ketones Organic Building Blocks AMINE Carbonyl Compounds C13 to C14 Building Blocks Building Blocks C13 to C14 Carbonyl Compounds Chemical Synthesis Organic Building Blocks Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals FINE Chemical & INTERMEDIATES Aromatic Benzophenones & Derivatives (substituted) Various Metabolites and Impurities Nitrazepam Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals C13 to C14 Carbonyl Compounds Ketones