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ChemicalBook >> CAS DataBase List >>Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- Structure
Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- structure
CAS No.
1034305-17-3
Chemical Name:
Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-
Synonyms
2-(5-BroMo-2-fluorobenzyl)benzothiophene;2-(5-BroMo-2-fluorobenzyl)benzo[b]thiophene;Ipragliflozin-004;Azilsartan Impurity 64;Ipragliflozin Impurity B;Ipragliflozin Impurity 9;Ipragliflozin intermediate 1;Ipragliflozin impurity B (B4);2-[(5-broMo-2-fluorophenyl)Methyl]-;2-(5-Eromo-2-fluorobenzyl)benzobthiophene
CBNumber:
CB82652155
Molecular Formula:
C15H10BrFS
Molecular Weight:
321.21
MDL Number:
MFCD28144826
MOL File:
1034305-17-3.mol
MSDS File:
SDS
Last updated:2026-01-07 11:19:19
Product description Number Pack Size Price
2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene B961545 100mg $175
2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene B961545 50mg $110
2-(5-Bromo-2-fluorobenzyl)benzo[B]thiophene 3115AH 1g $123
2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97% A111765 5g $153
2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 95%+ CM130309 5g $205
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Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- Properties

Boiling point 408.9±35.0 °C(Predicted)
Density 1.509±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
Appearance White to off-white Solid
InChI InChI=1S/C15H10BrFS/c16-12-5-6-14(17)11(7-12)9-13-8-10-3-1-2-4-15(10)18-13/h1-8H,9H2
InChIKey IKGTVOQAJKYBGO-UHFFFAOYSA-N
SMILES C12=CC=CC=C1C=C(CC1=CC(Br)=CC=C1F)S2

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B961545 2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 1034305-17-3 100mg $175 2021-12-16 Buy
TRC B961545 2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 1034305-17-3 50mg $110 2021-12-16 Buy
AK Scientific 3115AH 2-(5-Bromo-2-fluorobenzyl)benzo[B]thiophene 1034305-17-3 1g $123 2021-12-16 Buy
Ambeed A111765 2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97% 1034305-17-3 5g $153 2021-12-16 Buy
Chemenu CM130309 2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 95%+ 1034305-17-3 5g $205 2021-12-16 Buy
Product number Packaging Price Buy
B961545 100mg $175 Buy
B961545 50mg $110 Buy
3115AH 1g $123 Buy
A111765 5g $153 Buy
CM130309 5g $205 Buy

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- Chemical Properties,Uses,Production

Uses

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- is mainly used in medicine and organic synthesis.

Synthesis

Benzo[b]thiophene-2-Methanol, α-(5-broMo-2-fluorophenyl)-

1034305-11-7

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-

1034305-17-3

General procedure for the synthesis of 2-(5-bromo-2-fluorobenzyl)benzo[b]thiophene from benzo[b]thiophen-2-yl(5-bromo-2-fluorophenyl)methanol: 35.4 g (105 mmol) of benzo[b]thiophene-2-yl(5-bromo-2-fluorophenyl)methanol, a compound of Formula 3, was dissolved in 800 mL of dichloromethane, and the solution was cooled to -20 °C. To this solution, 36.5 mL (230 mmol) of triethylsilane and 15.2 mL (120 mmol) of boron trifluoride ethyl ether compound were slowly added under stirring. The reaction mixture was kept stirred at -20°C for 30 minutes. Upon completion of the reaction, saturated aqueous sodium bicarbonate solution was added to the mixture to neutralize the reaction. The organic phase was separated, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by column chromatography (eluent: ethyl acetate/hexane mixed solvent) to afford the target product 2-(5-bromo-2-fluorobenzyl)benzo[b]thiophene (Compound 4) 30.4 g, with 99.5% purity and 90.1% yield.

References

[1] Patent: CN108276396, 2018, A. Location in patent: Paragraph 0041; 0048; 0049; 0064; 0079
[2] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 10, p. 3263 - 3279
[3] Patent: CN108623558, 2018, A. Location in patent: Paragraph 0042; 0044; 0046; 0048; 0050; 0052; 0054; 0056

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- Preparation Products And Raw materials

Raw materials

Benzo[b]thiophene-2-Methanol, α-(5-broMo-2-fluorophenyl)- Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)chloroMethyl]- Triethylsilane Boron trifluoride diethyl etherate Dichloromethane

Preparation Products

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- Suppliers

Global( 165)Suppliers
Supplier Tel Email Country ProdList Advantage
ANHUI CHICO CHEMICAL CO., LTD.
+8613057662806 kirsten@chicopharm.com China 1323 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21597 55
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838 chloewu@chicopharm.cn CHINA 340 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29833 58
Biochempartner 		0086-13720134139 candy@biochempartner.com CHINA 965 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10405 58
Supplier Advantage
ANHUI CHICO CHEMICAL CO., LTD.
58
Capot Chemical Co.,Ltd. 		60
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Yingrui Biopharma Co., Ltd. 		60
Nanjing Finetech Chemical Co., Ltd. 		55
Anqing Chico Pharmaceutical Co., Ltd. 		58
career henan chemical co 		58
Biochempartner 		58
Shenzhen Nexconn Pharmatechs Ltd 		58

View Lastest Price from Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(5-Bromo-2-fluorobenzyl)benzothiophene pictures 2026-02-02 2-(5-Bromo-2-fluorobenzyl)benzothiophene
1034305-17-3
 US $0.00 / kg 1kg 99% 100mt/year Jinan Finer Chemical Co., Ltd
Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- pictures 2025-11-18 Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-
1034305-17-3
 US $1.10 / g 1g 99.0% Min 100 Tons Dideu Industries Group Limited
2-(5-Bromo-2-fluorobenzyl)benzothiophene pictures 2025-04-04 2-(5-Bromo-2-fluorobenzyl)benzothiophene
1034305-17-3
 US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

1034305-17-3(Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-)Related Search:

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Ipragliflozin-004 Ipragliflozin Impurity B 2-(5-BroMo-2-fluorobenzyl)benzo[b]thiophene 2-(5-bromo-2-fluorobenzyl)-1-benzothiophene 2-[(5-bromo-2-fluorophenyl)methyl]-1-benzothiophene Ipragliflozin impurity B (B4) 2-[(5-broMo-2-fluorophenyl)Methyl]- Ipragliflozin intermediate 1 Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- 2-(5-BroMo-2-fluorobenzyl)benzothiophene 2-[(5-bromo-2-fluorophenyl)Methyl]-Benzo[b]thiophene Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- ISO 9001：2015 REACH Azilsartan Impurity 64 Ipragliflozin Impurity 9 2-(5-Eromo-2-fluorobenzyl)benzobthiophene 1034305-17-3 C15H10BrFS