IQGAP1 antibody
- CAS No.
- Chemical Name:
- IQGAP1 antibody
- Synonyms
- IQGAP1 antibody
- CBNumber:
- CB85648326
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| IQGAP1 Antibody | orb622692 | 50μl | $400 |
| IQGAP1 Antibody | orb622692 | 100μl | $540 |
| IQGAP1 Antibody | orb380108 | 100μl | $360 |
| IQGAP1 antibody Affinity purified by Protein A | orb10931 | 200μg | $673.2 |
| IQGAP1 antibody Affinity purified by Protein A | orb10931 | 100μg | $421.6 |
IQGAP1 antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb622692 | IQGAP1 Antibody | 50μl | $400 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb622692 | IQGAP1 Antibody | 100μl | $540 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb380108 | IQGAP1 Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb10931 | IQGAP1 antibody Affinity purified by Protein A | 200μg | $673.2 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb10931 | IQGAP1 antibody Affinity purified by Protein A | 100μg | $421.6 | 2021-12-16 | Buy |
IQGAP1 antibody Chemical Properties,Uses,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Hamster;Monkey
Background
IQGAPs are scaffolding proteins involved in mediating cytoskeletal function. They contain multiple protein interaction domains and bind to a growing number of molecules including actin, myosin light chain, calmodulin, E-cadherin, and β-catenin. Through their GAP-related domains, they bind the small GTPases Rac1 and cdc42. IQGAPs lack GAP activity, however, and regulate small GTPases by stabilizing their GTP-bound forms. Research studies have shown that the function and distribution of the IQGAP proteins widely vary. IQGAP1 is ubiquitously expressed and has been found to interact with APC and the CLIP170 complex in response to small GTPases, promoting cell polarization and migration. Additional research studies have suggested that IQGAP1 could play a part in the invasiveness of some cancers. IQGAP2, which is about 60% identical to IQGAP1, is expressed primarily in liver, but lower levels have been detected in the prostate, kidney, thyroid, stomach, and testis. Research studies have shown that IQGAP2 displays tumor suppressor properties. Less is known about the function of IQGAP3, but this protein is present in the lung, brain, small intestine, and testis and is only expressed in proliferating cells, suggesting a role in cell growth and division.
References
[1] Briggs, M.W. and Sacks, D.B. (2003) EMBO Rep 4, 571-4.
[2] Ho, Y.D. et al. (1999) J Biol Chem 274, 464-70.
[3] Brill, S. et al. (1996) Mol Cell Biol 16, 4869-78.
[4] Watanabe, T. et al. (2004) Dev Cell 7, 871-83.
[5] Fukata, M. et al. (2002) Cell 109, 873-85.
[6] Chew, C.S. et al. (2005) Am J Physiol Gastrointest Liver Physiol 288, G376-87.
[7] Jin, S.H. et al. (2008) Int J Cancer 122, 1040-6.
[8] Liu, Z. et al. (2010) Clin Cancer Res 16, 6009-18.
[9] Wang, S. et al. (2007) J Cell Sci 120, 567-77.
[10] Schmidt, V.A. et al. (2003) Blood 101, 3021-8.
IQGAP1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
IQGAP1 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Novus Biologicals | 400821347 | orders@novusbio.com | China | 6433 | 58 |
| Shanghai Qierqi Biotech Co., Ltd. | 027-19371278702 18008634902 | ruihening88@163.com | China | 3009 | 58 |
| GeneTex, Inc. | 0755-26755892 1-949-553-1900 | international@genetex.com | China | 6092 | 58 |
| NSJ Bioreagents | 858.663.9055 8586639055 | NSJBioname@qq.com | China | 6941 | 58 |
| Enzo Biochem Inc | Enzo Biochem Inc. 13797054060 | Enzoname@qq.com | China | 6174 | 58 |
| Cell Signaling Technology Inc | 21-80243558 86218024 | info@cellsignal.cn | China | 6725 | 58 |
| Abmart Inc | 4006-123-828 13162017139 | market@ab-mart.com | China | 6917 | 58 |
| Wuhan Fine Biotech Co Ltd | 13047170542 | marketing@fn-test.com | China | 6600 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 6051 | 58 |
| Rockland Immunochemicals Inc | 0512-65829739 | antibodies-onlinename@qq.com | China | 6808 | 58 |
| Supplier | Advantage |
|---|---|
| Novus Biologicals | 58 |
| Shanghai Qierqi Biotech Co., Ltd. | 58 |
| GeneTex, Inc. | 58 |
| NSJ Bioreagents | 58 |
| Enzo Biochem Inc | 58 |
| Cell Signaling Technology Inc | 58 |
| Abmart Inc | 58 |
| Wuhan Fine Biotech Co Ltd | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 58 |
| Rockland Immunochemicals Inc | 58 |
