ウリジン5'-二りん酸(α-D-グルコピラノシル)二ナトリウム 化学特性,用途語,生産方法
効能
肝保護薬
説明
Uridine 5'-diphosphoglucose disodium salt, secreted by
cardiomyocytes during ischemia and reperfu, is a potent agonist of the
proinflammatory P2Y14 receptor. It acts an important role in the
regulation of inflammation and neutrophil polarization in neutrophils.
Uridine 5’-diphosphoglucose disodium salt is also the precursor of
glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms.
Uridine 5’-diphosphoglucose disodium salt is promising for research in
counteracting myocardial infarction/reperfusion (MIR)-induced
inflammation in the heart tissue.
使用
Uridine 5'-diphosphoglucose disodium salt is a phosphorylated uridine derivative used in nucleotide sugars metabolism as an activated form of glucose as a substrate for the enzyme glucosyltransferases. It is used in the treatment of chronic alco holism. It is used in characterization of limonoid glucosyltransferase.
主な応用
Uridine 5'-diphosphoglucose disodium salt is a key component of metabolism. As the "activated" form of glucose, it directly participates in a variety of biochemical reactions. "Disodium salt" refers to its stable, water-soluble form in the laboratory, where two sodium ions (Na+) balance the molecule's charge. UDP-G is the primary glucose donor for building energy reserves (glycogen), structural components in plants, and converting glucose into other essential sugars (such as galactose), while also playing a crucial role in detoxification.
一般的な説明
Uridine diphosphate glucose (UDP-glucose) is a glycogen precursor. The transfer of glucose from UDP-glucose to growing glycogen chain is catalyzed by the enzyme glycogen synthase. The enzyme uridine diphosphate galactose-4-epimerase catalyzes the formation of UDP-glucose from UDP-galactose.
Biochem/physiol Actions
Uridine diphosphate glucose (UDP-glucose) is an essential mediator of the cellular metabolic pathways. In yeast, the high levels of trehalose and glycogen favor increased levels of UDP-glucose.
ウリジン5'-二りん酸(α-D-グルコピラノシル)二ナトリウム 上流と下流の製品情報
原材料
準備製品