ACE 031 化学特性,用途語,生産方法
使用
ACE 031 is a muscle modulator that combines with myostatin and other negative regulators of muscle mass to promote muscle growth. It is a fusion protein of activin receptor type IIB (ActRIIB) and IgG1-Fc that binds to myostatin and related ligands. Clinical studies have shown that ACE 031 can be used to treat myopathies such as Duchenne muscular dystrophy (DMD).
参考文献
[1] Craig Campbell. “Myostatin inhibitor ACE-031 treatment of ambulatory boys with Duchenne muscular dystrophy: Results of a randomized, placebo-controlled clinical trial.” Muscle & Nerve 55 4 (2017): 458–464.
[2] Joonho Suh, Yun-Sil Lee. “Myostatin Inhibitors: Panacea or Predicament for Musculoskeletal Disorders?” Journal of Bone Metabolism 27 3 (2020): 151–165.
ACE 031 上流と下流の製品情報
原材料
準備製品