Setipiprant manufacturers and suppliers

Setipiprant suppliers

Setipiprant

CAS:: 866460-33-5

MF:: C24H19FN2O3

MW:: 402.42

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Properties

Boiling point:: 690.4±55.0 °C(Predicted)

Density: 1.37±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

solubility: DMSO:48.67(Max Conc. mg/mL);120.94(Max Conc. mM)
DMF:50.0(Max Conc. mg/mL);124.25(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.24(Max Conc. mM)
Ethanol:3.0(Max Conc. mg/mL);7.45(Max Conc. mM)

form: A solid

pka: 4.24±0.10(Predicted)

color: Light yellow to yellow

InChI: InChI=1S/C24H19FN2O3/c25-16-8-9-21-19(12-16)20-13-26(11-10-22(20)27(21)14-23(28)29)24(30)18-7-3-5-15-4-1-2-6-17(15)18/h1-9,12H,10-11,13-14H2,(H,28,29)

InChIKey: IHAXLPDVOWLUOS-UHFFFAOYSA-N

SMILES: N1(CC(O)=O)C2=C(C=C(F)C=C2)C2CN(C(C3=C4C(C=CC=C4)=CC=C3)=O)CCC1=2

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P305+P351+P338

Use

Setipiprant, also known as ACT-129968 and KYTH-105, is a potent and selective CRTH2 antagonist. Setipiprant at multiple oral doses was well tolerated and reduced both the allergen-induced LAR and the associated AHR in allergic asthmatics. Setipiprant may be a promising target for the treatment of allergic disorders.

You can find Setipiprant suppliers, manufacturers, and distributors from countries such as China, United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.