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ChemicalBook >> CAS DataBase List >> RAS INHIBITORY PEPTIDE

RAS INHIBITORY PEPTIDE

RAS INHIBITORY PEPTIDE price.
  • $68 - $1308.62
  • Product name: RAS INHIBITORY PEPTIDE
  • CAS: 159088-48-9
  • MF: C53H91N19O11
  • MW: 1170.41
  • EINECS:
  • MDL Number:MFCD00237248
  • Synonyms:RAS INHIBITORY PEPTIDE;VPPPVPPRRR-NH2;VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG;H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH;HSOS (1149-1158) N10 SH3 BINDING DOMAIN;Sos SH3 domain inhibitor;L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-;Sos SH3 domain inhibitor inhibitor
9 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Usbiological
Package
  • 500μg
  • 1mg
  • 5MG
  • 10mg
  • ManufacturerAK Scientific
  • Product number2952CC
  • Product descriptionRasinhibitorypeptide
  • Packaging1mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2952CC
  • Product descriptionRasinhibitorypeptide
  • Packaging10mg
  • Price$1065
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPEP0003028
  • Product descriptionRAS INHIBITORY PEPTIDE 95.00%
  • Packaging1MG
  • Price$721.59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPEP0003028
  • Product descriptionRAS INHIBITORY PEPTIDE 95.00%
  • Packaging5MG
  • Price$1308.62
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17474
  • Product descriptionRas Inhibitory Peptide ≥95%
  • Packaging500μg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17474
  • Product descriptionRas Inhibitory Peptide ≥95%
  • Packaging1mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17474
  • Product descriptionRas Inhibitory Peptide ≥95%
  • Packaging5mg
  • Price$502
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17474
  • Product descriptionRas Inhibitory Peptide ≥95%
  • Packaging10mg
  • Price$869
  • Updated2024-03-01
  • Buy
  • ManufacturerUsbiological
  • Product numberR1198-40
  • Product descriptionRas Inhibitory Peptide
  • Packaging1mg
  • Price$531
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2952CC Rasinhibitorypeptide 1mg $226 2021-12-16 Buy
AK Scientific 2952CC Rasinhibitorypeptide 10mg $1065 2021-12-16 Buy
American Custom Chemicals Corporation PEP0003028 RAS INHIBITORY PEPTIDE 95.00% 1MG $721.59 2021-12-16 Buy
American Custom Chemicals Corporation PEP0003028 RAS INHIBITORY PEPTIDE 95.00% 5MG $1308.62 2021-12-16 Buy
Cayman Chemical 17474 Ras Inhibitory Peptide ≥95% 500μg $68 2024-03-01 Buy
Cayman Chemical 17474 Ras Inhibitory Peptide ≥95% 1mg $116 2024-03-01 Buy
Cayman Chemical 17474 Ras Inhibitory Peptide ≥95% 5mg $502 2024-03-01 Buy
Cayman Chemical 17474 Ras Inhibitory Peptide ≥95% 10mg $869 2024-03-01 Buy
Usbiological R1198-40 Ras Inhibitory Peptide 1mg $531 2021-12-16 Buy

Properties

Density :1.52±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: Miscible; PBS (pH 7.2): 10 mg/ml
form :A crystalline solid
pka :3.31±0.10(Predicted)
Sequence :Val-Pro-Pro-Pro-Val-Pro-Pro-Arg-Arg-Arg

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.

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