Welcome to chemicalbook!
China English Japan Germany
010-86108875
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
RFQ
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> Tipiracil hydrochloride

Tipiracil hydrochloride

Tipiracil hydrochloride price.
  • $5 - $2060
  • Product name: Tipiracil hydrochloride
  • CAS: 183204-72-0
  • MF: C9H12Cl2N4O2
  • MW: 279.12318
  • EINECS:
  • MDL Number:MFCD01571384
  • Synonyms:Tipiracil (hydrochloride);2,4(1H,3H)-PyriMidinedione,5-chloro-6-[(2-iMino-1-pyrrolidinyl)Methyl] hydrochloride;5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione monohydrochloride;Tipiracil HCl;5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione,hydrochloride;5-Chloro-6-(2-iminopyrrolidin-1-ylmethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione hydrochloride;5-Chloro-6-(2-iminopyrrolidin-1-ylmethyl)uracil hydrochloride;Tipiracil hydrochloride(TPI)
Price39 Properties Safety Information Description
39 prices
Selected condition：
Brand
  • AccelPharmtech
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1MG
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 10mM(in 1mL H2O)
  • 2g
  • 5g
  • 10G
  • 25G
  • 100G
  • ManufacturerAccelPharmtech
  • Product numberWW1462
  • Product descriptionTipiracilhydrochloride 99.00%
  • Packaging10G
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberWW1462
  • Product descriptionTipiracilhydrochloride 99.00%
  • Packaging25G
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberWW1462
  • Product descriptionTipiracilhydrochloride 99.00%
  • Packaging100G
  • Price$2060
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3751BB
  • Product descriptionTipiracilhydrochloride
  • Packaging100mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0318825
  • Product description5-CHLORO-6-(2-IMINO-PYRROLIDIN-1-YLMETHYL)-1H-PYRIMIDINE-2,4-DIONE HYDROCHLORIDE 95.00%
  • Packaging1MG
  • Price$582.12
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3875
  • Product descriptionTipiracilhydrochloride
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3875
  • Product descriptionTipiracilhydrochloride
  • Packaging10mM(in 1mL H2O)
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3875
  • Product descriptionTipiracilhydrochloride
  • Packaging10mg
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3875
  • Product descriptionTipiracilhydrochloride
  • Packaging25mg
  • Price$271
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3875
  • Product descriptionTipiracilhydrochloride
  • Packaging50mg
  • Price$371
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS020122
  • Product description5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98%
  • Packaging5mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS020122
  • Product description5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98%
  • Packaging10mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS020122
  • Product description5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98%
  • Packaging25mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS020122
  • Product description5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98%
  • Packaging50mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS020122
  • Product description5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98%
  • Packaging100mg
  • Price$18
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS020122
  • Product description5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98%
  • Packaging250mg
  • Price$27
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech WW1462 Tipiracilhydrochloride 99.00% 10G $360 2021-12-16 Buy
AccelPharmtech WW1462 Tipiracilhydrochloride 99.00% 25G $660 2021-12-16 Buy
AccelPharmtech WW1462 Tipiracilhydrochloride 99.00% 100G $2060 2021-12-16 Buy
AK Scientific 3751BB Tipiracilhydrochloride 100mg $77 2021-12-16 Buy
American Custom Chemicals Corporation HCH0318825 5-CHLORO-6-(2-IMINO-PYRROLIDIN-1-YLMETHYL)-1H-PYRIMIDINE-2,4-DIONE HYDROCHLORIDE 95.00% 1MG $582.12 2021-12-16 Buy
ApexBio Technology A3875 Tipiracilhydrochloride 5mg $100 2021-12-16 Buy
ApexBio Technology A3875 Tipiracilhydrochloride 10mM(in 1mL H2O) $105 2021-12-16 Buy
ApexBio Technology A3875 Tipiracilhydrochloride 10mg $142 2021-12-16 Buy
ApexBio Technology A3875 Tipiracilhydrochloride 25mg $271 2021-12-16 Buy
ApexBio Technology A3875 Tipiracilhydrochloride 50mg $371 2021-12-16 Buy
Arctom AS020122 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98% 5mg $5 2021-12-16 Buy
Arctom AS020122 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98% 10mg $6 2021-12-16 Buy
Arctom AS020122 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98% 25mg $8 2021-12-16 Buy
Arctom AS020122 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98% 50mg $10 2021-12-16 Buy
Arctom AS020122 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98% 100mg $18 2021-12-16 Buy
Arctom AS020122 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dionehydrochloride ≥98% 250mg $27 2021-12-16 Buy
Next Last

Properties

Melting point :245℃ (decomposition)
storage temp. :2-8°C
solubility :DMSO (Slightly, Heated), Water (Slightly)
form :powder
color :white to beige
Water Solubility :H2O: 5mg/mL, clear (warmed)
Stability :Hygroscopic
InChI :InChI=1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H
InChIKey :KGHYQYACJRXCAT-UHFFFAOYSA-N
SMILES :C1(=O)NC(CN2CCCC2=N)=C(Cl)C(=O)N1.[H]Cl

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Tipiracil (TPI) is a potent and competitive inhibitor of thymidine phosphorylase (TPase) with an IC50 value of 35 nM for human placental TPase. It is selective for TPase over other pyrimidine-metabolizing enzymes (IC50s = >1 mM for UPase, OPRTase, TK, and DPDase). TPI inhibits the phosphorolysis and degradation of trifluorothymidine , a cytotoxic nucleoside, in human breast and colon carcinoma tumor samples. Oral administration of TPI (12.5-50 mg/kg) enhances the anti-tumor activity of trifluorothymidine in a mouse AZ-521 stomach cancer xenograft model. Formulations containing TPI have been used for the treatment of metastatic colorectal cancer.

More related product prices

Posaconazole Levetiracetam 7544-75-4 6-(Chloromethyl)uracil methyl 5-chloro-2,6-dioxo-3H-pyrimidine-4-carboxylate

Related product price

Suppliers and manufacturers

career henan chemical co
Tipiracil
$1.00 /1kg
Tipiracil CAS: 183204-72-0
TargetMol Chemicals Inc.
Tipiracil hydrochloride
$43.00 /5mg
Tipiracil hydrochloride CAS:183204-72-0
Beijing Cooperate Pharmaceutical Co.,Ltd
ATK CHEMICAL COMPANY LIMITED
Lianyungang happen teng technology co., LTD
Biochempartner
Beijing Ribio Biotech Co.,Ltd
BOC Sciences
Alchem Pharmtech,Inc.
Antai Fine Chemical Technology Co.,Limited