1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER synthesis
- Product Name:1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
- CAS Number:4498-68-4
- Molecular formula:C10H10N2O2
- Molecular Weight:190.2
99-87-6
253 suppliers
$16.00/25mL
4492-02-8
88 suppliers
$19.00/250mg
4498-68-4
118 suppliers
$16.00/100mg
Yield:-
Reaction Conditions:
palladium
Steps:
5 Indazole-3-Carboxylic Acid
Preparation 5 Indazole-3-Carboxylic Acid A mixture of 4,5,6,7-tetrahydroindazole-3-carboxylic acid ethyl ester (21.0 g, 108 mmol), 5% palladium on carbon (7.0 g solid, 3.29 mmol of Pd), and 210 mL of cymene was heated to reflux for 38 hours. At this point complete conversion to the indazole-3-carboxylic acid ethyl ester was shown by TLC (silica gel, 3:1 ethyl acetate-heptane). The reaction was cooled to 120° C. and the 5% palladium on carbon was removed by filtration.
References:
Eli Lilly and Company US6069152, 2000, A
623-73-4
152 suppliers
$26.70/5g
88284-48-4
172 suppliers
$9.00/250mg
4498-68-4
118 suppliers
$16.00/100mg
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](http://hg.y866.cn/chemistry/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
0 suppliers
inquiry
4498-68-4
118 suppliers
$16.00/100mg
623-73-4
152 suppliers
$26.70/5g
88284-48-4
172 suppliers
$9.00/250mg
7716-35-0
3 suppliers
inquiry
4498-68-4
118 suppliers
$16.00/100mg
64-17-5
824 suppliers
$10.00/50g
4498-67-3
489 suppliers
$6.00/5g
4498-68-4
118 suppliers
$16.00/100mg