ChemicalBook CAS DataBase List 4-(TRIFLUOROMETHOXY)BENZENESULPHONYLACETONITRILE

4-(TRIFLUOROMETHOXY)BENZENESULPHONYLACETONITRILE synthesis

1synthesis methods

Product Name:4-(TRIFLUOROMETHOXY)BENZENESULPHONYLACETONITRILE
CAS Number:217186-16-8
Molecular formula:C9H6F3NO3S
Molecular Weight:265.21

169685-29-4 Synthesis

169685-29-4
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4-(TRIFLUOROMETHOXY)BENZENESULPHONYLACETONITRILE

217186-16-8
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 2 h
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 °C / Inert atmosphere

References:

Anderson, Marc O.;Zhang, Jicheng;Liu, Yan;Yao, Chenjuan;Phuan, Puay-Wah;Verkman [Journal of Medicinal Chemistry,2012,vol. 55,# 12,p. 5942 - 5950]

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