Promestriene synthesis

Yield:-

Steps:

Multi-step reaction with 3 steps
1: hydrogen bromide / acetone / 24 h / 55 °C / Inert atmosphere
2: methanol / 12 h / 64 °C / Inert atmosphere
3: potassium iodide; potassium carbonate / methanol / 24 h / 64 °C

References:

Beijing Jincheng Tyre Pharmaceutical Co., Ltd.;Beijing Jincheng Tyre Pharmaceutical Co., Ltd. Cangzhou Fen Corporation;You Yaxin;Zhang Zhongzheng;Zhang Bin;Zhang Guobin;Zhang Zhizhong;Zhang Tong;Li Zongqi CN110218234, 2019, A

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