Prostaglandin E1 synthesis
- Product Name:Prostaglandin E1
 - CAS Number:745-65-3
 - Molecular formula:C20H34O5
 - Molecular Weight:354.48
 
                        
                        125180-07-6
                        
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                        745-65-3
                        
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Yield:-
Steps:
                    Multi-step reaction with 5 steps
1: 93 percent / DMSO, (COCl)2 / CH2Cl2 / -60 °C
2: 92 percent / 1,2-dimethoxy-ethane / 0 °C
3: (S)-BINAL-H / tetrahydrofuran / -100 - -78 °C
4: 1.) m-CPBA, 2.) NH4Cl, H2O / 1.) CH2Cl2, 0 deg C
5: 72 percent / 0.1 M phosphate buffer / Baker's yeast, pH 7.0
                
References:
Hwu;Robl;Gilbert [Journal of the American Chemical Society,1992,vol. 114,# 8,p. 3125 - 3126]
                        
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                        745-65-3
                        
                        449 suppliers
                        
                        $19.00/1mg