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品牌:MedChemExpress (MCE)
Drug_Names:Mosunetuzumab
Catalog_No:HY-P99033
CAS:1905409-39-3
产品活性:Mosunetuzumab (BTCT-4465A) 是一种人源化、基于免疫球蛋白 G1 的双特异性抗体,靶向 CD20 (B 细胞) 和 CD3 (T 细胞)。Mosunetuzumab 重定向 T 细胞以接合和消除恶性 B 细胞,可用于研究复发或难治性 (R/R) B 细胞非霍奇金淋巴瘤 (B-NHL)[1]。
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性: Mosunetuzumab (BTCT-4465A) 是一种基于免疫球蛋白 G1 的人源化双特异性抗体,靶向 CD20(B 细胞)和 CD3(T 细胞)。 Mosunetuzumab 重定向 T 细胞以参与和消除恶性 B 细胞,可用于研究复发或难治性 (R/R) B 细胞非霍奇金淋巴瘤 (B-NHL)[1]。
热销产品:Delta-like 1/DLL1, Human (HEK293, His) | Angiopoietin-2, Mouse (HEK293, Fc) | BRD4, Human (His-Flag) | CutA, Human (His) | Fc gamma RIIIB/CD16b, Human (192a.a, HEK293, His) | CREG1/CREG, Mouse (HEK293, His) | PDCD8/AIFM1, Human (His) | Beta-galactosidase/GLB1, E.coli | Complement C3/C3a, Mouse | Cystatin C/CST3, Human (HEK293, His) | Cystatin A/CSTA, Human (His) | C-Reactive, Human (His) | Serum Albumin/ALB, Human (P.pastoris) | Fructose-bisphosphate aldolase A/ALDOA, Human (C-His) | CD3D, Human (HEK293, His) | DNA polymerase beta, Human (His) | CD45, Mouse (HEK293, His) | Collagen alpha-1(III) chain/COL3A, Mouse (HEK293, His) | PTPRC/CD45RA, Human (HEK293, His) | Cryptic, Human (HEK293, His) |
热门产品线:重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物 | 寡核苷酸
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:
Lihua E Budde, et al. Single-Agent Mosunetuzumab Shows Durable Complete Responses in Patients With Relapsed or Refractory B-Cell Lymphomas: Phase I Dose-Escalation Study. J Clin Oncol. 2022 Feb 10;40(5):481-491.