本公司提供科研EPCR/CD201内皮细胞活化蛋白受体抗体,抗体质量可靠,订购EPCR/CD201内皮细胞活化蛋白受体抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称:内皮细胞活化蛋白受体抗体 英文名称:Anti-EPCR/CD201 货号:bs-9506R 抗体来源:兔 克隆类型:多克隆 蛋白分子量:predicted molecular weight: 27kDa 纯化方法:affinity purified by Protein A 交叉反应:hu, rat, mo 测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍:EPCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. It is an N glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. It is expressed strongly in the endothelial cells of arteries and veins in heart and lung. It is overexpressed in several human non-Pgp multidrug resistant (MDR) tumor cell lines. Whether and how anti-coagulant and anti-inflammatory functions of EPCR facilitate oncogenesis and/or drug resistance is unclear.Subcellular Location : Cell Membrane