\n 本公司提供科研HLA B/HLA G人类白细胞抗原G抗体HLA B/HLA G人类白细胞抗原G抗体,抗体质量可靠,订购HLA B/HLA G人类白细胞抗原G抗体HLA B/HLA G人类白细胞抗原G抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:人类白细胞抗原G抗体人类白细胞抗原G抗体
英文名称:Anti-HLA B/HLA GAnti-HLA B/HLA G
货号:bs-0752R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 35kDa
纯化方法:affinity purified by Protein A
交叉反应:hu
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Human Leukocyte Antigen-G, (Human Leukocyte Antigen-G, Human Leukocyte Antigen-G (HLA-G) is an atypical leukocyte antigen group Ⅰhistocompatibility antigen. Antigen that under normal circumstances, only in the human placenta Expression. Pathology in the case of HLA-G expression only in certain cancer cells in normal tissues are rare benign tumor or expression. Therefore, HLA-G is a high degree of tumor-specific tumor marker. Research in recent years that the HLA - G as a molecular immune tolerance in tumor immune escape may play an important role.Subunit : Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Homodimer; disulfide-linked. Binds to LILRB1 and LILRB2.Subcellular Location : Membrane; Single-pass type I membrane protein.Tissue Specificity : Expressed in trophoblasts.Similarity : Belongs to the MHC class I family.Contains 1 Ig-like C1-type (immunoglobulin-like)人类白细胞抗原G/组织相容性白细胞抗原G(Human Leukocyte Antigen-G, HLA-G )是一种非典型的白细胞抗原Ⅰ族组织相溶性抗原。该抗原在正常情况下仅在胎盘的绒毛膜表达。在病理情况下HLA-G只在某些癌细胞表达,在正常组织或良性肿瘤则很少表达.因此, HLA-G是一个具有高度肿瘤特异性的肿瘤标志物。 近年研究认为HLA—G作为免疫耐受分子,在肿瘤免疫逃逸中可能具有重要作用.产品图片