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Gold-catalyzed enantioselective functionalization of indoles
Pierre Milcendeau,Nazarii Sabat,Xavier Guinchard
Organic & Biomolecular Chemistry Pub Date : 07/23/2020 00:00:00 , DOI:10.1039/D0OB01245A
Abstract

Gold catalysis and indole chemistry are two mature and prolific fields. The gold-catalyzed functionalization of indoles has produced numerous results and paved the way for novel strategies in the building of molecular complexity. However – and curiously – though enantioselective gold catalysis is now a well-established field, it has been relatively little applied to the modification of indoles. This review highlights most of the enantioselective gold-catalyzed examples of the functionalization of indoles in order to emphasize the strengths and limitations of the method.

Graphical abstract: Gold-catalyzed enantioselective functionalization of indoles
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