A Pd(ii)-catalyzed C–H activation approach to densely functionalized N-heteroaromatics related to neocryptolepine and their evaluation as potential inducers of apoptosis†,10.1039/C5RA06764B

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

A Pd(ii)-catalyzed C–H activation approach to densely functionalized N-heteroaromatics related to neocryptolepine and their evaluation as potential inducers of apoptosis†

Rajnikanth Sunke,Vimal Kumar,Mohd Ashraf Ashfaq,E. V. Venkat Shivaji Ramarao,Nasreen Z. Ehtesham,Manojit Pal

RSC Advances Pub Date : 05/04/2015 00:00:00 , DOI:10.1039/C5RA06764B

Abstract

11-Carboxymethyl substituted 6H-indolo[2,3-b]quinolines, which are potential inducers of apoptosis, were obtained by one-pot Pd(II)-catalyzed intramolecular oxidative C3–H alkenylation of the indole ring of (E)-alkyl-3-(2-(1H-indol-2-ylamino)phenyl)acrylate derivatives followed by desulfonylation.