钙离子通道阻断剂，也称为钙离子通道拮抗剂，是一类可以减缓钙离子通过钙离子通道进入心脏和血管壁细胞的化合物。钙离子会导致心脏和动脉收缩。通过阻断钙离子进入，钙通道阻滞剂可以让血管松弛和打开。因此钙通道阻滞剂通常用于降低血压，缓解胸痛(心绞痛)和心律失常等。
Chem960可以提供钙离子通道阻断剂和拮抗剂，所有小分子化合物均明确报道对钙离子通道均有抑制作用。Chem960钙离子通道阻断剂库是开发降压药物进行心血管疾病研究的有用工具。
• A unique collection of 151 calcium channel blockers and antagonists for high throughput screening (HTS) and high content screening (HCS).
• A useful tool for the discovery of antihypertensive drugs and anti-cardiovascular drugs.
• Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.
• Structurally diverse, medicinally active, and cell permeable.
• Detailed compound information with structure, IC50, and brief introduction.
• High purity and quality validated by NMR and LC/MS.
• All compounds are in stock and continuously updated.
