Astragalin
紫云英苷(Kaempferol-3-glucoside)
CAS: 480-10-4
化学式: C21H20O11
| 中文名 | 紫云英苷 |
| 英文名 | Kaempferol-3-glucoside |
| 别名 | 黄芪苷 紫云英苷 紫云英甙 百蕊草素II 紫云英苷对照品, 莰非醇-3-O-葡萄糖苷 ASTRAGALINE 紫云英苷 莫西沙星杂质K(莫西沙星杂质5) ASTRAGALINE 紫云英苷 标准品 紫云英苷(黄芪苷,莰非醇-3-O-葡萄糖苷,山柰酚-3-葡萄糖苷,百蕊草素Ⅱ) |
| 英文别名 | k5 ASTRAGALIN astragalin astragaline KAEMPFEROL-3-GLUCOSIDE Kaempferol-3-glucoside KAEMPFEROL-3-O-GLUCOSIDE Kaempferol-3-O-glucoside KAEMPFEROL-3-O-BETA-D-GLUCOPYRANOSIDE 4h-1-benzopyran-4-one,3-(beta-d-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyp 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl beta-D-glucopyranoside 3-(β-D-Glucopyranosyloxy)-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
| CAS | 480-10-4 |
| 化学式 | C21H20O11 |
| 分子量 | 448.38 |
| InChI | InChI=1/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-26,28-29H,7H2/t13-,15-,17+,18-,21+/m1/s1 |
| InChIKey | JPUKWEQWGBDDQB-QSOFNFLRSA-N |
| 密度 | 1.79±0.1 g/cm3(Predicted) |
| 熔点 | 223-229°C |
| 沸点 | 823.2±65.0 °C(Predicted) |
| 比旋光度 | +16.9 (c, 0.62 in MeOH) |
| 闪点 | 291.5°C |
| 蒸汽压 | 1.09E-28mmHg at 25°C |
| 溶解度 | 易溶于DMSO，甲醇氯仿的混合溶剂，可溶于热甲醇，不溶于石油醚。 |
| 折射率 | 1.774 |
| 酸度系数 | 6.20±0.40(Predicted) |
| 存储条件 | Sealed in dry,Store in freezer, under -20°C |
| 外观 | 整洁 |
| 物化性质 | 易溶于DMSO，甲醇氯仿的混合溶剂，可溶于热甲醇，不溶于石油醚。 来源于百蕊草 |
| MDL号 | MFCD00075932 |
| 安全术语 | 22 - 切勿吸入粉尘。 |
| WGK Germany | 3 |
| RTECS | DJ3080000 |
| 海关编号 | 29389090 |
| 参考资料 展开查看 | 1. 郭伟 滕亮 万琪臻 等. HPLC双波长法同时测定意大利牛舌草中3种成分的含量[J]. 西北药学杂志 2018 033(001):28-32. 2. 汪慧 钱巧珍 王静 等. HPLC法同时测定地锦草中芦丁 异槲皮苷 紫云英苷的含量[J]. 中华灾害救援医学 2015 003(009):509-511. 3. 杨海洋 刘洋 李梦薇 等. HPLC法同时测定辣木叶颗粒中异槲皮苷、紫云英苷和丹酚酸B的含量[J]. 中国药房 2019 30(09):17-20. 4. 李梦薇, 顾文宏, 张久旭,等. 基于中心复合-响应面二次模型优化辣木叶改善睡眠复方提取工艺[J]. 辽宁中医药大学学报, 2018, 020(007):73-76. 5. 陈鸣, 安昌, 杨成梓,等. 基于性状描述及紫云英苷含量的野鸦椿子质量评价[J]. 海峡药学, 2019, 031(003):34-37. 6. 许佳明, 赵安琦, 谢静,等. 应用高效逆流色谱分离桑叶黄酮类化合物[J]. 分析试验室, 2019, 038(003):266-269. 7. 张久旭, 刘洋, 李梦薇,等. 辣木叶通便复方对小鼠通便作用的研究[J]. 中医药学报, 2019, 47(002):33-37. 8. 张娟 卿德刚 孙宇 等. 化学计量学辅助分析罗布麻中的黄酮类成分[J]. 西北药学杂志 2020 035(002):173-177. 9. 闫征, 吴寒, 黄午阳,等. 杀青工艺对蓝莓叶茶活性成分及其抗氧化性能的影响[J]. 安徽农业科学, 2019. 10. 尹秀文, 侯成波, 陈江鹏,等. 采用在体单向肠灌流模型研究荷叶多成分整体的肠渗透性[J]. 中国中药杂志, 2017, 42(008):1525-1531. 11. 杜庆鑫, 魏艳秀, 刘攀峰,等. 杜仲雄花主要活性成分含量的多样性[J]. 林业科学, 2017, 053(002):35-43. 12. 杜庆鑫, 魏艳秀, 李钦,等. 杜仲雄花生长发育动态及活性成分量变化[J]. 中草药, 2017, 048(013):2746-2751. 13. 杜庆鑫,刘攀峰,魏艳秀,庆军,杜红岩.基于主成分与聚类分析的杜仲雄花品质综合评价[J].植物研究,2016,36(06):846-852+859. 14. 姚鑫,诸炜荣,黄宏亮,曾燕如,喻卫武.掌叶覆盆子药用有效成分变异与优良种质筛选[J].中国中药杂志,2021,46(03):575-581. 15. 张月,唐钦悦,代娟,魏香奕,颜佳利,江岩.桑叶黄酮提取物制备及其体外抗氧化作用研究[J].中国食品添加剂,2020,31(09):47-52. 16. Xiao-Xu Han, Ya-Ping Jiang, Ning Liu, Jing Wu, Jia-Mei Yang, Yu-Xiang Li, Miao Sun, Tao Sun, Ping Zheng, Jian-Qiang Yu, Protective effects of Astragalin on spermatogenesis in streptozotocin-induced diabetes in male mice by improving antioxidant activity a 17. Qiang Zhang, Ruiyun Huo, Yibo Ma, Shuangmei Yan, Lei Yang, Fengli Chen,A novel microwave-assisted steam distillation approach for separation of essential oil from tree peony (Paeonia suffruticosa Andrews) petals: Optimization, kinetic, chemical compositio 18. Liu, Tongji, et al. "Improvement effect of lotus leaf flavonoids on carbon tetrachloride-induced liver injury in mice." Biomedicines 8.2 (2020): 41.http://doi.org/10.3390/biomedicines8020041 19. Liu, Chanmin, et al. "Flavonoid-rich extract of Paulownia fortunei flowers attenuates diet-induced hyperlipidemia, hepatic steatosis and insulin resistance in obesity mice by AMPK pathway." Nutrients 9.9 (2017): 959.http://doi.org/10.3390/nu9090959 20. Cao, Yanni, et al. "Chemical fingerprint and multicomponent quantitative analysis for the quality evaluation of Cyclocarya paliurus leaves by HPLC–Q–TOF–MS." Molecules 22.11 (2017): 1927.http://doi.org/10.3390/molecules22111927 21. Wu, Ya, et al. "Anti‐obesity effect of Liupao tea extract by modulating lipid metabolism and oxidative stress in high‐fat‐diet‐induced obese mice." Journal of Food Science 86.1 (2021): 215-227. 22. Yang, Wei, et al. "Liquid chromatography–mass spectrometry-based metabolomics analysis of flavonoids and anthraquinones in Fagopyrum tataricum L. Gaertn.(tartary buckwheat) seeds to trace morphological variations." Food chemistry 331 (2020): 127354.http:/ 23. Gao, Mingliang, et al. "Evaluation of VEGF mediated pro-angiogenic and hemostatic effects and chemical marker investigation for Typhae Pollen and its processed product." Journal of Ethnopharmacology 268 (2021): 113591.http://doi.org/10.1016/j.jep.2020.113 24. Yang, Jing, et al. "Comparisons of the active components in four unripe raspberry extracts and their activites." Food Science and Technology 39 (2019): 632-639.http://doi.org/10.1590/fst.27418 25. [IF=4.451] Jianzhong Zhu et al."In-vitro inhibitory effects of flavonoids in Rosa roxburghii and R. sterilis fruits on α-glucosidase: Effect of stomach digestion on flavonoids alone and in combination with acarbose."J Funct Foods. 2019 Mar;54:13 26. [IF=4.411] Yanni Cao et al."Chemical Fingerprint and Multicomponent Quantitative Analysis for the Quality Evaluation of Cyclocarya paliurus Leaves by HPLC–Q–TOF–MS."Molecules. 2017 Nov;22(11):1927 27. [IF=4.171] Chanmin Liu et al."Flavonoid-Rich Extract of Paulownia fortunei Flowers Attenuates Diet-Induced Hyperlipidemia, Hepatic Steatosis and Insulin Resistance in Obesity Mice by AMPK Pathway."Nutrients. 2017 Sep;9(9):959 28. [IF=4.098] Chunlin Li et al."Rapid and non-destructive discrimination of special-grade flat green tea using Near-infrared spectroscopy."Spectrochim Acta A. 2019 Jan;206:254 29. [IF=3.743] Xiao-Xu Han et al."Protective effects of Astragalin on spermatogenesis in streptozotocin-induced diabetes in male mice by improving antioxidant activity and inhibiting inflammation."Biomed Pharmacother. 2019 Feb;110:561 30. [IF=6.306] Wei Yang et al."Liquid chromatography–mass spectrometry-based metabolomics analysis of flavonoids and anthraquinones in Fagopyrum tataricum L. Gaertn. (tartary buckwheat) seeds to trace morphological variations."Food Chem. 2020 Nov;331:127354 31. [IF=5.81] Mu Jianfei et al."Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UHPLC-QqQ-MS) and Comparison of Their Anti-Aging Effects."Fro 32. [IF=5.645] Zhang-Zhen Bai et al."Comparative investigation on metabolites and biological activities of Paeonia ostii stamens from different geographical regions of China."Ind Crop Prod. 2021 Nov;172:114038 33. [IF=5.279] Qinggang Yin et al."Identification of Specific Glycosyltransferases Involved in Flavonol Glucoside Biosynthesis in Ginseng Using Integrative Metabolite Profiles, DIA Proteomics, and Phylogenetic Analysis."J Agr Food Chem. 2021;69(5):1714–1726 34. [IF=4.952] Yuxin Hao et al."Stability and mechanism of phenolic compounds from raspberry extract under in vitro gastrointestinal digestion."Lwt Food Sci Technol. 2021 Mar;139:110552 35. [IF=4.759] Fengli Chen et al."Magnetically stabilized bed packed with synthesized magnetic silicone loaded with ionic liquid particles for efficient enrichment of flavonoids from tree peony petals."J Chromatogr A. 2020 Feb;1613:460671 36. [IF=4.36] Li Lin et al."Study on the alleviation of Fengshi Gutong capsule on rheumatoid arthritis through integrating network pharmacology and experimental exploration."J Ethnopharmacol. 2021 Nov;280:114471 37. [IF=4.36] Mingliang Gao et al."Evaluation of VEGF mediated pro-angiogenic and hemostatic effects and chemical marker investigation for Typhae Pollen and its processed product."J Ethnopharmacol. 2021 Mar;268:113591 38. [IF=4.24] Nana Li et al."Characterization of phenolic compounds and anti-acetylcholinase activity of coconut shells."Food Biosci. 2021 Aug;42:101204 39. [IF=4.169] Zhang Zhen et al."Foliar Spraying of 6-Benzylaminopurine Promotes Growth and Flavonoid Accumulation in Mulberry (Morus alba L.)."Journal Of Plant Growth Regulation. 2021 Jul 15 40. [IF=4.098] Chunlin Li et al."Discrimination of white teas produced from fresh leaves with different maturity by near-infrared spectroscopy."Spectrochim Acta A. 2020 Feb;227:117697 41. [IF=3.167] Ya Wu et al."Anti-obesity effect of Liupao tea extract by modulating lipid metabolism and oxidative stress in high-fat-diet-induced obese mice."J Food Sci. 2021 Jan;86(1):215-227 42. [IF=2.633] Yanni Cao et al."Seasonal Variation in Phenolic Compounds and Antioxidant Activity in Leaves of Cyclocarya paliurus (Batal.) Iljinskaja."Forests. 2019 Aug;10(8):624 43. [IF=2.245] Hu Xuequan et al."Anti-inflammatory Effect of Astragalin and Chlorogenic Acid on Escherichia coli-Induced Inflammation of Sheep Endometrial Epithelium Cells."Front Vet Sci. 2020 Apr;7:201 44. [IF=2.19] Sheng-xiang Yang et al."Extraction of flavonoids from Cyclocarya paliurus (Juglandaceae) leaves using ethanol/salt aqueous two-phase system coupled with ultrasonic."J Food Process Pres. 2020 Jun;44(6):e14469 45. [IF=1.908] Lin Zheng et al."Comparative pharmacokinetics of quercitrin, astragalin, afzelin and taxifolin in plasma after oral administration of Polygonum orientale inflorescence in sham-operated and myocardial ischemia–reperfusion injury rats."Xenobiotica. 2020;50 46. [IF=6.057] Qi Tong et al.Biosynthesis-based spatial metabolome of Salvia miltiorrhiza Bunge by combining metabolomics approaches with mass spectrometry-imaging.Talanta. 2021 Nov;:123045 47. [IF=1.312] Xiaoran Zhao et al."Discrimination of Cuscuta chinensis Lam. and Cuscuta japonica Choisy based on a combination of chemometrics and fingerprint classification."Journal Of Liquid Chromatography & Related Technologies. 2022 Jan 09 48. [IF=6.576] Guowei Man et al."Profiling Phenolic Composition in Pomegranate Peel From Nine Selected Cultivars Using UHPLC-QTOF-MS and UPLC-QQQ-MS."Front Nutr. 2021; 8: 807447 49. [IF=3.373] Yiyuan Luo et al."Quality evaluation of Tetrastigma hemsleyanum different parts based on quantitative analysis of 42 bioactive constituents combined with multivariate statistical analysis."PHYTOCHEMICAL ANALYSIS. 2022 Apr 05 50. [IF=3.24] YanShou Shi et al."Seasonal variation influences flavonoid biosynthesis path and content, and antioxidant activity of metabolites in Tetrastigma hemsleyanum Diels & Gilg."PLoS One. 2022 Apr;17(4):e0265954 51. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177 52. [IF=4.294] Yang Hu et al."Astragalin attenuates AlCl3/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation."NEUROTOXICOLOGY. 2022 Jul;91:60 53. [IF=6.953] Yanqing Yang et al."The hypoglycemic and hypolipemic potentials of Moringa oleifera leaf polysaccharide and polysaccharide-flavonoid complex."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2022 May;: 54. [IF=5.396] Xiaoqin Zhang et al."Chimonanthus salicifolius attenuated vascular remodeling by alleviating endoplasmic reticulum stress in spontaneously hypertensive rat."Food & Function. 2022 May;: 55. [IF=5.34] Mingliang Gao et al."Discovery of processing-associated Q-marker of carbonized traditional Chinese medicine: an integrated strategy of metabolomics, systems pharmacology and in vivo high-throughput screening model."PHYTOMEDICINE. 2022 May;:154152 56. [IF=6.486] Ping Zheng et al."Comparative analyses of American and Asian lotus genomes reveal insights into petal color, carpel thermogenesis and domestication."PLANT JOURNAL. 2022 Apr 01 |
Astragalin - 简介
紫云英苷是一种常见的化学物质，化学名称为Anthocyanin。以下是关于紫云英苷的性质，用途，制法和安全信息的介绍：
性质：
- 紫云英苷是一种天然存在于植物中的紫红色或蓝色色素。
- 它是一种类黄酮类化合物，具有强烈的抗氧化作用。
- 紫云英苷在酸性环境下呈红色，而在碱性环境下呈蓝色。
- 它是水溶性的，可以溶解在水中形成溶液。
用途：
制法：
- 紫云英苷可以从一些水果和蔬菜中提取得到，如葡萄、蓝莓、紫薯等。提取方法通常涉及破碎、过滤和浓缩等步骤。
安全信息：
- 紫云英苷属于天然物质，一般认为对人体较为安全。
- 但对于特定人群，如过敏体质的人或存在特定疾病的人，可能引起过敏反应或不良影响。
性质：
- 紫云英苷是一种天然存在于植物中的紫红色或蓝色色素。
- 它是一种类黄酮类化合物，具有强烈的抗氧化作用。
- 紫云英苷在酸性环境下呈红色，而在碱性环境下呈蓝色。
- 它是水溶性的，可以溶解在水中形成溶液。
用途：
制法：
- 紫云英苷可以从一些水果和蔬菜中提取得到，如葡萄、蓝莓、紫薯等。提取方法通常涉及破碎、过滤和浓缩等步骤。
安全信息：
- 紫云英苷属于天然物质，一般认为对人体较为安全。
- 但对于特定人群，如过敏体质的人或存在特定疾病的人，可能引起过敏反应或不良影响。
最后更新：2024-04-09 15:16:50
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产品名: Astragaline 去供应商网站查看 询盘CAS: 480-10-4
产地: 美国
包装: A649305
规格: 50μL, 1mL, 1mg, 5mg, 10mg, 50mg
价格: 139, 732, 163, 343, 488, 1170
库存: 现货
电话: 400-920-2911
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微信: 18721517911
产品描述: Astragaline是一种从 Nelumbo nucifera Gaertn.(莲花)的叶子中分离和纯化的类黄酮,具有抗炎活性.
现货供应
产品名: 5,7-二羟基-2-(4-羟基苯基)-3-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)-4H-苯并吡喃-4-酮 询盘CAS: 480-10-4
产地: 上海
包装: 100mg；1g；250mg；25mg；50mg
规格: 98%
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库存: 现货
电话: 400-968-2212
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QQ: 3623107365
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产品描述: 5,7-二羟基-2-(4-羟基苯基)-3-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)-4H-苯并吡 更多
提供多种规格现货供应
产品名: 紫云英苷(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IA05601
产地: 北京
包装: 1ml/瓶
规格: IA05601-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 18101056239(微信同号)
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QQ: 3193328036
微信: 18101056239
产品描述: 产品覆盖：小分子化合物、分析对照品、染色试剂、生化试剂盒、细胞生物学、分子生物学、抗体、蛋白、多肽、ELISA试剂盒、微生物培养、化学合成、仪器耗材、CRO技术 更多
提供多种规格现货供应
产品名: Astragalin 去供应商网站查看 询盘CAS: 480-10-4
产地: 美国
包装: 5 mg;10 mg;25 mg
规格: HY-N0015R
库存: 询盘
电话: 021-38924433; 021-58955995
手机: 18019480960
电子邮件: sales@medchemexpress.cn
产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度: ≥98%
产品名: Astragaline 去供应商网站查看 询盘
CAS: 480-10-4
产地: 美国
包装: A649305
规格: 50μL, 1mL, 1mg, 5mg, 10mg, 50mg
价格: 139, 732, 163, 343, 488, 1170
库存: 现货
电话: 400-920-2911
手机: 18721517911
电子邮件: sales@ambeed.cn
微信: 18721517911
产品描述: Astragaline是一种从 Nelumbo nucifera Gaertn.(莲花)的叶子中分离和纯化的类黄酮,具有抗炎活性.
CAS: 480-10-4
产地: 美国
包装: A649305
规格: 50μL, 1mL, 1mg, 5mg, 10mg, 50mg
价格: 139, 732, 163, 343, 488, 1170
库存: 现货
电话: 400-920-2911
手机: 18721517911
电子邮件: sales@ambeed.cn
微信: 18721517911
产品描述: Astragaline是一种从 Nelumbo nucifera Gaertn.(莲花)的叶子中分离和纯化的类黄酮,具有抗炎活性.
现货供应
产品名: 5,7-二羟基-2-(4-羟基苯基)-3-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)-4H-苯并吡喃-4-酮 询盘CAS: 480-10-4
产地: 上海
包装: 100mg；1g；250mg；25mg；50mg
规格: 98%
价格: 电话、微信、QQ、邮件
库存: 现货
电话: 400-968-2212
手机: 18916960931
电子邮件: 3623107365@qq.com
QQ: 3623107365
微信: 18916960931
产品描述: 5,7-二羟基-2-(4-羟基苯基)-3-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)-4H-苯并吡 更多
产品名: 紫云英苷(10mM in DMSO,无菌) 去供应商网站查看 询盘
CAS: IA05601
产地: 北京
包装: 1ml/瓶
规格: IA05601-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 18101056239(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 18101056239
产品描述: 产品覆盖：小分子化合物、分析对照品、染色试剂、生化试剂盒、细胞生物学、分子生物学、抗体、蛋白、多肽、ELISA试剂盒、微生物培养、化学合成、仪器耗材、CRO技术 更多
CAS: IA05601
产地: 北京
包装: 1ml/瓶
规格: IA05601-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 18101056239(微信同号)
电子邮件: 3193328036@qq.com
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产品描述: 产品覆盖：小分子化合物、分析对照品、染色试剂、生化试剂盒、细胞生物学、分子生物学、抗体、蛋白、多肽、ELISA试剂盒、微生物培养、化学合成、仪器耗材、CRO技术 更多
产品名: Astragalin 去供应商网站查看 询盘
CAS: 480-10-4
产地: 美国
包装: 5 mg;10 mg;25 mg
规格: HY-N0015R
库存: 询盘
电话: 021-38924433; 021-58955995
手机: 18019480960
电子邮件: sales@medchemexpress.cn
产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度: ≥98%
CAS: 480-10-4
产地: 美国
包装: 5 mg;10 mg;25 mg
规格: HY-N0015R
库存: 询盘
电话: 021-38924433; 021-58955995
手机: 18019480960
电子邮件: sales@medchemexpress.cn
产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度: ≥98%
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