古伦朴根碱
药根碱(Jatrorrhizine)
CAS: 3621-38-3
化学式: C20H20INO4
| 中文名 | 药根碱 |
| 英文名 | Jatrorrhizine |
| 别名 | 药根碱 藥根鹼 古伦朴根碱 药根碱(标准品) 药根碱, 来源于功劳叶 JATRORRHIZINE 药根碱 JATRORRHIZINE 药根碱 标准品 |
| 英文别名 | Neprotin Neprotine Yatrorizine Jatrorrhizin Jatrorrhizine 2,9,10-trimethoxy- 5,6-Dihydro-3-hydroxy-2,9,10-trimethoxyberbinium Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy- 3-hydroxy-2,9,10-trimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium 2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol 2,9,10-Trimethoxy-5,6-Dihydroisoquinolino[2,1-B]Isoquinolin-7-Ium-3-Ol |
| CAS | 3621-38-3 |
| EINECS | 222-817-3 |
| 化学式 | C20H20INO4 |
| 分子量 | 465.28 |
| InChI | InChI=1/C20H19NO4/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3/h4-5,8-11H,6-7H2,1-3H3/p+1 |
| InChIKey | MXTLAHSTUOXGQF-UHFFFAOYSA-O |
| 熔点 | 208～210℃ |
| 溶解度 | 甲醇 (微溶加热) |
| 存储条件 | Inert atmosphere,2-8°C |
| 稳定性 | 吸湿性 |
| 外观 | 固体 |
| 颜色 | Orange |
| 物化性质 | 外观性状：红黄色针状结晶 熔点：208℃～210℃ 溶解性：溶于水和乙醇 |
| MDL号 | MFCD01310242 |
| 危险品标志 | N - 危害环境的物品 |
| 风险术语 | 50 - 对水生生物有极高毒性。 |
| 安全术语 | 61 - 避免释放至环境中。参考特别说明/安全数据说明书。 |
| 危险品运输编号 | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| 参考资料 展开查看 | 1. 林才志, 张贇赟, 段雪琳,等. 壮药汗衣台抗HBV有效成分分析及对HBVDNA、HBVcccDNA的影响[J]. 中药药理与临床, 2018, v.34;No.193(01):59-64. 2. 王书宁, 祝洪艳, 郜玉钢,等. 黄藤总生物碱回流提取工艺的优化[J]. 中成药, 2018, 040(006):1399-1403. 3. 张赟赟,李嘉.HPLC-ESI-MS/MS法同时测定金线风中7种有效成分[J].中华中医药杂志,2017,32(06):2762-2764. 4. 严赟, 张赟赟. HPLC-ESI-MS/MS同时测定金果榄中5种成分含量[J]. 中药材, 2017, 40(002):395-398. 5. 皮文霞 朱鑫仙 方婷 等. HPLC同时测定"三热论"方各纯化部位中药根碱、表小檗碱、黄连碱、巴马汀和小檗碱的含量[J]. 中国实验方剂学杂志 2012 18(14):110-113. 6. 李听弦, 李蒙, 张志,等. 基于高效液相色谱指纹图谱及红外光谱评价黄连及其炮制品质量差异[J]. 中南药学, 2019, 017(004):556-560. 7. 张久旭, 范晶, 李小阳,等. 基于内在品质的黄连药材现代产地加工方法研究[J]. 辽宁中医药大学学报, 2019, v.21;No.185(09):74-77. 8. 李听弦 李蒙 张志 等. 一测多评法测定不同味连饮片中6个生物碱类成分的含量[J]. 药物分析杂志 2018 038(007):1132-1138. 9. 纪万里,周泽华,王婷婷,安叡,梁琨,王新宏.基于UPLC-LTQ-Orbitrap-MS方法分析半夏泻心汤化学成分[J].药物分析杂志,2020,40(10):1736-1750. 10. Zhu, Ling, et al. "Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition." Food and chemical toxicology 50.7 (2012): 2584-2588.http://doi.org/10.1016/j.fct.2012.04.0 11. Wang, Kun, et al. "Identification of metabolites of palmatine in rats after oral administration using ultra‐high‐performance liquid chromatography/quadrupole time‐of‐flight mass spectrometry." Rapid Communications in Mass Spectrometry 31.6 (2017): 523-537. 12. Wang, Kun, et al. "Metabolites identification of berberine in rats using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry." Journal of pharmaceutical and biomedical analysis 139 (2017): 73-86.http://doi.org/10.1016/ 13. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.http:// 14. [IF=6.057] Zhihong Li et al."New MS network analysis pattern for the rapid identification of constituents from traditional Chinese medicine prescription Lishukang capsules in vitro and in vivo based on UHPLC/Q-TOF-MS."Talanta. 2018 Nov;189:606 15. [IF=6.023] Ling Zhu et al."Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition."Food Chem Toxicol. 2012 Jul;50:2584 16. [IF=4.759] Yanyan Zhang et al."Rapid screening and identification of monoamine oxidase-A inhibitors from Corydalis Rhizome using enzyme-immobilized magnetic beads based method."J Chromatogr A. 2019 May;1592:1 17. [IF=4.411] Jinjun Shan et al."Liquid Chromatography Coupled with Linear Ion Trap Hybrid OrbitrapMass Spectrometry for Determination of Alkaloids in Sinomeniumacutum."Molecules. 2018 Jul;23(7):1634 18. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239 19. [IF=3.935] Kun Wang et al."Metabolites identification of berberine in rats using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry."J Pharmaceut Biomed. 2017 May;139:73 20. [IF=3.361] Huanyu Guan et al."Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out 21. [IF=2.882] Kun Wang et al."Identification of berberrubine metabolites in rats by using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry."Fitoterapia. 2018 Jan;124:23 22. [IF=2.419] Kun Wang et al."Identification of metabolites of palmatine in rats after oral administration using ultra-high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry."Rapid Commun Mass Sp. 2017 Mar;31(6):523-537 23. [IF=1.618] Li Jiang-Yan et al."Seasonal Variation of Alkaloid Contents and Anti-Inflammatory Activity of Rhizoma coptidis Based on Fingerprints Combined with Chemometrics Methods."J Chromatogr Sci. 2015 Aug;53(7):1131-1139 24. [IF=11.413] Sifan Luo et al."Rapid identification and isolation of neuraminidase inhibitors from mockstrawberry (Duchesnea indica Andr.) based on ligand fishing combined with HR-ESI-Q-TOF-MS."Acta Pharm Sin B. 2020 Oct;10:1846 25. [IF=3.963] Zhong-min Zhao et al."Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine."Pestic Biochem Phys. 2019 Sep;159:51 26. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820 27. [IF=3.463] Xiao-Meng Liu et al."Comparative transcriptome analysis provides novel insights into the molecular mechanism of berberine biosynthesis in Coptis chinensis."Sci Hortic-Amsterdam. 2022 Jan;291:110585 28. [IF=3.004] Kai Zhang et al."Untargeted metabolomics reveals the synergistic mechanisms of Yuanhu Zhitong oral liquid in the treatment of primary dysmenorrhea."J Chromatogr B. 2021 Feb;1165:122523 29. [IF=2.351] Juanjuan Liu et al."Antifungal evaluation of traditional herbal monomers and their potential for inducing cell wall remodeling in Candida albicans and Candida auris."Biofouling. 2020;36(3):319-331 30. [IF=5.165] Juanning Ren et al."Qualitative and quantitative analysis of multi-components in Xing-Su-Ning Capsules for quality improvement."Arab J Chem. 2022 Jun;15:103825 |
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产品名: Jatrorrhizine药根碱 标准品 去供应商网站查看 询盘CAS: 3621-38-3
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提供多种规格现货供应
产品名: Jatrorrhizine药根碱 标准品 去供应商网站查看 询盘CAS: 3621-38-3
产地: 北京
包装: 瓶
规格: SJ8010-20mg,20mg,IJ0020-5mg,5mg,IJ0020-10mg,10mg,IJ0020-20mg,20mg
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 18101056239(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 18101056239
产品描述: 产品覆盖：小分子化合物、分析对照品、染色试剂、生化试剂盒、细胞生物学、分子生物学、抗体、蛋白、多肽、ELISA试剂盒、微生物培养、化学合成、仪器耗材、CRO技术 更多
现货供应
产品名: Jatrorrhizine 去供应商网站查看 询盘CAS: 3621-38-3
产地: 美国
包装: 询盘
规格: HY-N0749
价格: 询价
库存: 询盘
电话: 021-38924433; 021-58955995
手机: 18019480960
电子邮件: sales@medchemexpress.cn
产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度:
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