小诺米星
硫酸小诺霉素(Micronomicin Sulfate)
CAS: 66803-19-8
化学式: C20H43N5O11S
| 中文名 | 硫酸小诺霉素 |
| 英文名 | Micronomicin Sulfate |
| 别名 | 小诺米星 沙加霉素 硫酸小诺霉素 硫酸相模霉素 硫酸小诺米星 硫酸沙加霉素 小诺霉素(标准品) |
| 英文别名 | Micronomicin Sulfate MICRONOMYCIN SULFATE MICRONOMICIN SULFATE Micronomycin sulfate sulfate,d-1-6))-2-deoxy Micronomicin sulfate JAS1998 6'-N-METHYLGENTAMICIN C1A HEMIPENTASULFATE streptamine,o-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-d-erythro-hexop yranosyl-(1-4)-o-(3-deoxy-4-c-methyl-3-(methylamino)-beta-l-arabinopyranosyl-( Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy-, sulfate, D- D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-a-D-erythro-hexopyranosyl-(14)-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(16)]-2-deoxy-, sulfate (salt) (9CI) |
| CAS | 66803-19-8 |
| EINECS | 1308068-626-2 |
| 化学式 | C20H43N5O11S |
| 分子量 | 561.65 |
| InChI | InChI=1/C20H41N5O7.H2O4S/c1-20(28)8-29-19(14(27)17(20)25-3)32-16-12(23)6-11(22)15(13(16)26)31-18-10(21)5-4-9(30-18)7-24-2;1-5(2,3)4/h9-19,24-28H,4-8,21-23H2,1-3H3;(H2,1,2,3,4)/t9-,10+,11-,12+,13-,14+,15+,16-,17+,18+,19+,20-;/m0./s1 |
| 熔点 | >205°C (dec.) |
| 沸点 | 667℃ |
| 闪点 | >110°(230°F) |
| 水溶性 | Freely soluble in water |
| 蒸汽压 | 1.19E-20mmHg at 25°C |
| 溶解度 | DMSO (非常轻微，加热，超声处理)，水 (轻微) |
| 存储条件 | Hygroscopic, Refrigerator, under inert atmosphere |
| 稳定性 | 吸湿性 |
| 外观 | 固体 |
| 颜色 | White to Pale Yellow |
| 体外研究 | Micronomicin has a potent antibacterial activity, it is active against Staphylococcus aureus FDA 209 P, Staphylococcus aureus with the minimal inhibitory values of 0.01 μg/ml. It is also against Escherichia coli St.M. 589, Baker 2, F 14-BK, and R5/W677 with the minimal inhibitory values of 0.75 μg/ml, 0.3 μg/ml, 0.03 μg/ml and 0.03 μg/ml. And it is active against Pseudomonas aeruginosa strains and lebsiella pneumoniae strains (MICs = 0.03-17.5 μg/ml). |
| 体内研究 | Micronomicin sulfate is highly active against various bacterial infections in mice, and has an intravenous acute LD 50 in mice of 93 mg/kg.Micronomicin sulfate (intravenous injection; 4-100 mg/kg; 30 days) is injected for subacute toxicity study. The wistar rats dies at the dose level of 100 mg/kg (10 out of 30 animals): renal disorders and ataxia. The renal histological disorders occurrs mainly at the dose levels of 25 mg/kg and over. Animal Model: Wistar rats Dosage: 4, 10, 25, 63 mg/kg and 100 mg/kg Administration: Intravenous injection; 30 days Result: Led to death of rat at 100 mg/kg. |
| RTECS | WK2196000 |
| 上游原料 | 淀粉 盐酸 |
供应商列表
现货供应
产品名: Micronomicin 去供应商网站查看 询盘CAS: 66803-19-8
产地: 美国
包装: 25 mg;50 mg;100 mg
规格: HY-108307
库存: 现货，货期：1-2天
电话: 021-38924433; 021-58955995
手机: 18019480960
电子邮件: sales@medchemexpress.cn
产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度: ≥98.0%
现货供应
产品名: Micronomicin 去供应商网站查看 询盘CAS: 66803-19-8
产地: 美国
包装: 25 mg;50 mg;100 mg
规格: HY-108307
库存: 现货，货期：1-2天
电话: 021-38924433; 021-58955995
手机: 18019480960
电子邮件: sales@medchemexpress.cn
产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度: ≥98.0%
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