黄藤素
黄藤素(Palmatine)
CAS: 3486-67-7
化学式: C21H22NO4+
| 中文名 | 黄藤素 |
| 英文名 | Palmatine |
| 别名 | 黄藤素 巴马汀 |
| 英文别名 | Palmatin Palmatine BRN 1555498 Berbericinine UNII-G50C034217 Common fibraurea stem O,O-Dimethyldemethyleneberberine 5-21-06-00202 (Beilstein Handbook Reference) 7,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxyberbinium Berbinium, 7,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy- 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo(a,g)quinolizinium Dibenzo(a,g)quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy- 2,3,9,10-tetramethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium 2,3,9,10-tetramethoxyisoquinolino[3,2-a]isoquinolin-7-ium hydrate |
| CAS | 3486-67-7 |
| 化学式 | C21H22NO4+ |
| 分子量 | 352.409 |
| InChI | InChI=1/C21H20NO4.H2O/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;/h5-12H,1-4H3;1H2/q+1 |
| 熔点 | 205°C |
| 溶解度 | 溶于水，甲醇 |
| 存储条件 | under inert gas (nitrogen or Argon) at 2-8°C |
| 外观 | 白色粉末 |
| 物化性质 | 来源于毛茛科植物黄连Coptis chinensis Franch |
| MDL号 | MFCD00221758 |
| 参考资料 展开查看 | 1. 闫宝琪, 董书伟, 王东升,等. 黄藤素对山羊子宫内膜上皮细胞的体外毒性研究[J]. 中国畜牧兽医, 2016, 43(012):3239-3244. 2. 张赟赟,李嘉.HPLC-ESI-MS/MS法同时测定金线风中7种有效成分[J].中华中医药杂志,2017,32(06):2762-2764. 3. 严赟, 张赟赟. HPLC-ESI-MS/MS同时测定金果榄中5种成分含量[J]. 中药材, 2017, 40(002):395-398. 4. 刘珍珍 白桥 徐皓. 不同初加工方法对延胡索5种生物碱含量的影响[J]. 现代农业科技 2019 000(022):173-176. 5. 晏余,陈维佳,赵岩,宗颖,时坤,何忠梅,杜锐.黄藤总生物碱固体分散体在小鼠体内吸收的药代动力学及相对生物利用度[J].吉林农业大学学报,2021,43(01):75-81. 6. Wang, Kun, et al. "Identification of metabolites of palmatine in rats after oral administration using ultra‐high‐performance liquid chromatography/quadrupole time‐of‐flight mass spectrometry." Rapid Communications in Mass Spectrometry 31.6 (2017): 523-537. 7. Nguyen, Thanh Xuan, et al. "Chitosan-coated nano-liposomes for the oral delivery of berberine hydrochloride." Journal of Materials Chemistry B 2.41 (2014): 7149-7159.http://doi.org/10.1039/C4TB00876F 8. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.http:// 9. [IF=6.331] Thanh Xuan Nguyen et al."Chitosan-coated nano-liposomes for the oral delivery of berberine hydrochloride."J Mater Chem B. 2014 Oct;2(41):7149-7159 10. [IF=6.057] Zhihong Li et al."New MS network analysis pattern for the rapid identification of constituents from traditional Chinese medicine prescription Lishukang capsules in vitro and in vivo based on UHPLC/Q-TOF-MS."Talanta. 2018 Nov;189:606 11. [IF=4.759] Yu-Xiu Yang et al."pH-dependent surface electrostatic effects in retention on immobilized artificial membrane chromatography: Determination of the intrinsic phospholipid-water sorption coefficients of diverse analytes."J Chromatogr A. 2018 Oct;1570:172 12. [IF=4.759] Yanyan Zhang et al."Rapid screening and identification of monoamine oxidase-A inhibitors from Corydalis Rhizome using enzyme-immobilized magnetic beads based method."J Chromatogr A. 2019 May;1592:1 13. [IF=4.411] Jinjun Shan et al."Liquid Chromatography Coupled with Linear Ion Trap Hybrid OrbitrapMass Spectrometry for Determination of Alkaloids in Sinomeniumacutum."Molecules. 2018 Jul;23(7):1634 14. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239 15. [IF=3.659] Rong Qian et al."In vitro and in vivo bactericidal activity of Tinospora sagittata (Oliv.) Gagnep. var. craveniana (S.Y.Hu) Lo and its main effective component, palmatine, against porcine Helicobacter pylori."Bmc Complem Altern M. 2016 Dec;16(1):1-8 16. [IF=2.896] Shun Liu et al."Effects of ultrahigh pressure extraction conditions on yields of berberine and palmatine from cortex Phellodendri amurensis."Anal Methods-Uk. 2013 Aug;5(17):4506-4512 17. [IF=1.618] Li Jiang-Yan et al."Seasonal Variation of Alkaloid Contents and Anti-Inflammatory Activity of Rhizoma coptidis Based on Fingerprints Combined with Chemometrics Methods."J Chromatogr Sci. 2015 Aug;53(7):1131-1139 18. [IF=5.81] Zhao Jing et al."Intra-Herb Interactions: Primary Metabolites in Coptidis Rhizoma Extract Improved the Pharmacokinetics of Oral Berberine Hydrochloride in Mice."Front Pharmacol. 2021 Jun;0:1426 19. [IF=3.963] Zhong-min Zhao et al."Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine."Pestic Biochem Phys. 2019 Sep;159:51 20. [IF=3.935] Yang Song et al."Pharmacokinetics, tissue distribution and plasma protein binding rate of palmatine following intragastric and intravenous administration in rats using liquid chromatography tandem mass spectrometry."J Pharmaceut Biomed. 2021 Sep;203:11422 21. [IF=3.463] Xiao-Meng Liu et al."Comparative transcriptome analysis provides novel insights into the molecular mechanism of berberine biosynthesis in Coptis chinensis."Sci Hortic-Amsterdam. 2022 Jan;291:110585 22. [IF=3.373] Xueyan Zhao et al."An integrated strategy for the establishment of a protoberberine alkaloid profile: Exploration of the differences in composition between Tinosporae radix and Fibraurea caulis."Phytochem Analysis. 2021 Nov;32(6):1131-1140 23. [IF=2.351] Juanjuan Liu et al."Antifungal evaluation of traditional herbal monomers and their potential for inducing cell wall remodeling in Candida albicans and Candida auris."Biofouling. 2020;36(3):319-331 24. [IF=1.345] Ya-Li Zhang et al."Coptisine suppresses proliferation and inhibits metastasis in human pancreatic cancer PANC-1 cells."J Asian Nat Prod Res. 2020;22(5):452-463 25. [IF=5.165] Juanning Ren et al."Qualitative and quantitative analysis of multi-components in Xing-Su-Ning Capsules for quality improvement."Arab J Chem. 2022 Jun;15:103825 |
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产品名: Palmatine掌叶防已碱 标准品 去供应商网站查看 询盘CAS: 3486-67-7
产地: 北京
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规格: SP8800-20mg,20mg,IP0850-20mg,20mg,IP0850-50mg,50mg,IP0850-100mg,100mg
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产品描述: 产品覆盖：小分子化合物、分析对照品、染色试剂、生化试剂盒、细胞生物学、分子生物学、抗体、蛋白、多肽、ELISA试剂盒、微生物培养、化学合成、仪器耗材、CRO技术 更多
提供多种规格现货供应
产品名: Palmatine掌叶防已碱 标准品 去供应商网站查看 询盘CAS: 3486-67-7
产地: 北京
包装: 瓶
规格: SP8800-20mg,20mg,IP0850-20mg,20mg,IP0850-50mg,50mg,IP0850-100mg,100mg
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 18101056239(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 18101056239
产品描述: 产品覆盖：小分子化合物、分析对照品、染色试剂、生化试剂盒、细胞生物学、分子生物学、抗体、蛋白、多肽、ELISA试剂盒、微生物培养、化学合成、仪器耗材、CRO技术 更多
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